Philipson Tomas, Linthicum Mark T, Snider Julia Thornton
Irving B. Harris School of Public Policy Studies, The University of Chicago, Chicago, Illinois.
Precision Health Economics, Los Angeles, California.
JPEN J Parenter Enteral Nutr. 2014 Nov;38(2 Suppl):5S-16S. doi: 10.1177/0148607114549770. Epub 2014 Sep 19.
As healthcare costs climb around the world, public and private payers alike are demanding evidence of a treatment's value to support approval and reimbursement decisions. Health economics and outcomes research, or HEOR, offers tools to answer questions about a treatment's value, as well as its real-world effects and cost-effectiveness. Given that nutrition interventions have to compete for space in budgets along with biopharmaceutical products and devices, nutrition is now increasingly coming to be evaluated through HEOR. This tutorial introduces the discipline of HEOR and motivates its relevance for nutrition. We first define HEOR and explain its role and relevance in relation to randomized controlled trials. Common HEOR study types--including burden of illness, effectiveness studies, cost-effectiveness analysis, and valuation studies--are presented, with applications to nutrition. Tips for critically reading HEOR studies are provided, along with suggestions on how to use HEOR to improve patient care. Directions for future research are discussed.
随着全球医疗成本的攀升,公共和私人支付方都要求提供治疗价值的证据,以支持审批和报销决策。卫生经济学与结果研究(HEOR)提供了工具,用于回答有关治疗价值及其实际效果和成本效益的问题。鉴于营养干预措施必须与生物制药产品和器械争夺预算空间,现在越来越多地通过HEOR对营养进行评估。本教程介绍了HEOR学科,并阐述了其与营养的相关性。我们首先定义HEOR,并解释其在随机对照试验中的作用和相关性。介绍了常见的HEOR研究类型,包括疾病负担研究、有效性研究、成本效益分析和估值研究及其在营养方面的应用。提供了批判性阅读HEOR研究的技巧,以及如何利用HEOR改善患者护理的建议。还讨论了未来的研究方向。