Taube F, Marczewski M, Norén J G
Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden.
J Dent. 2015 Feb;43(2):269-78. doi: 10.1016/j.jdent.2014.09.003. Epub 2014 Sep 18.
The purpose of this study was to discriminate hypomineralised enamel of permanent first molars from normal enamel by means of spectroscopic methods.
The present study was conducted using Multi spot Raman Fourier Transform Spectroscopy, Diffuse Reflectance Infrared Fourier Transform Spectroscopy (FTIR) and X-ray diffraction (XRD).
Raman spectroscopy indicated significantly more B-type carbonate and hydrocarbons in hypomineralised enamel diagnosed as MIH (Molar Incisor Hypomineralisation). From XRD analysis, no changes in crystallinity of the enamel apatite could be found.
Using multi spot Raman-spectroscopy, a significant molecular discrimination between normal and hypomineralised enamel could be made.
Detailed surface studies are needed in order to achieve better restorative materials, specifically designed for restoration of hypomineralised enamel, and are also needed in order to understand and predict the clinical consequences of hypomineralised enamel with the condition MIH.
本研究的目的是通过光谱方法区分恒牙第一磨牙矿化不足的牙釉质与正常牙釉质。
本研究采用多点拉曼傅里叶变换光谱、漫反射红外傅里叶变换光谱（FTIR）和X射线衍射（XRD）进行。
拉曼光谱表明，被诊断为MIH（磨牙切牙矿化不足）的矿化不足牙釉质中B型碳酸盐和碳氢化合物明显更多。通过XRD分析，未发现牙釉质磷灰石结晶度的变化。
使用多点拉曼光谱，可以对正常牙釉质和矿化不足牙釉质进行显著的分子区分。
为了获得专门设计用于修复矿化不足牙釉质的更好修复材料，需要进行详细的表面研究，同时也需要了解和预测患有MIH病症的矿化不足牙釉质的临床后果。
