Merry Callie R, Niland Courtney, Khalil Ahmad M
Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Methods Mol Biol. 2015;1206:1-14. doi: 10.1007/978-1-4939-1369-5_1.
Long noncoding RNAs are becoming increasingly appreciated as major players in gene regulation. They have been reported to play diverse roles in many biological processes. Here, we discuss their discovery, features, and known functions in cells. While not comprehensive, this chapter should serve to illustrate the power and promise of studying long noncoding RNAs.
长链非编码RNA作为基因调控的主要参与者正日益受到重视。据报道，它们在许多生物学过程中发挥着多种作用。在这里，我们讨论它们的发现、特征以及在细胞中的已知功能。虽然并不全面，但本章应有助于说明研究长链非编码RNA的力量和前景。
