de Góis Morais Paulo Leonardo Araújo, de Santana Melquisedec Abiaré Dantas, Cavalcante Judney Cley, de Oliveira Costa Miriam Stela Maris, Sousa Cavalcante Jeferson, do Nascimento Expedito Silva
Department of Morphology/Laboratory of Neuroanatomy, Biosciences Center, Federal University of Rio Grande do Norte, 59072-970 Natal, RN, Brazil.
Department of Physiology/Laboratory of Neurochemical Studies, Biosciences Center, Federal University of Rio Grande do Norte, 59072-970 Natal, RN, Brazil.
Neurosci Res. 2014 Dec;89:75-80. doi: 10.1016/j.neures.2014.08.016. Epub 2014 Sep 19.
The Zona Incerta is a key neural substrate of higher brain functions. A neural population in the caudal ZI projects into the superior colliculus. This recently has been identified as an important structure for the saccades. Applying CTb, we describe a retinal projection into the caudal ZI and the distribution of its terminal varicosities in the rock cavy, a Brazilian rodent, which has been used as an anatomical model to enhance the comprehension about the phylogeny of the nervous system. Contrary to other investigated rodents, the retinal fibers in the rock cavy lie in the caudal Zona Incerta (ZIc), suggesting a functional specialization in the rock cavy. The high resolution and qualitative analysis of retinal fibers in the present work provide a substrate to interpretation of the visual system, and its phylogenetic pathways among species.
未定带是高等脑功能的关键神经基质。未定带尾部的一群神经元投射到上丘。最近，上丘已被确定为眼球运动的重要结构。应用霍乱毒素亚基B（CTb），我们描述了巴西啮齿动物岩豚鼠视网膜向上丘尾部的投射及其终末膨体的分布，岩豚鼠已被用作解剖模型以增进对神经系统系统发育的理解。与其他研究过的啮齿动物不同，岩豚鼠的视网膜纤维位于未定带尾部（ZIc），这表明岩豚鼠具有功能特化。本研究对视网膜纤维进行的高分辨率和定性分析为解释视觉系统及其物种间的系统发育途径提供了基础。
