Kinoshita Naoki, Kita Akinobu, Takemura Akihiro, Nishimoto Yasuhiro, Adachi Toshiki
Department of Radiology, University of Fukui Hospital.
Nihon Hoshasen Gijutsu Gakkai Zasshi. 2014 Sep;70(9):877-82. doi: 10.6009/jjrt.2014_jsrt_70.9.877.
The uncertainty of the beam quality conversion factor (k(Q,Q0)) of standard dosimetry of absorbed dose to water in external beam radiotherapy 12 (JSMP12) is determined by combining the uncertainty of each beam quality conversion factor calculated for each type of ionization chamber. However, there is no guarantee that ionization chambers of the same type have the same structure and thickness, so there may be individual variations. We evaluated the uncertainty of k(Q,Q0) for JSMP12 using an ionization chamber dosimeter and linear accelerator without a specific device or technique in consideration of the individual variation of ionization chambers and in clinical radiation field. The cross calibration formula was modified and the beam quality conversion factor for the experimental values [(k(Q,Q0))field] determined using the modified formula. It's uncertainty was calculated to be 1.9%. The differences between (k(Q,Q0))field of experimental values and k(Q,Q0) for Japan Society of Medical Physics 12 (JSMP12) were 0.73% and 0.88% for 6- and 10-MV photon beams, respectively, remaining within ± 1.9%. This showed k(Q,Q0) for JSMP12 to be consistent with (k(Q,Q0))field of experimental values within the estimated uncertainty range. Although inter-individual differences may be generated, even when the same type of ionized chamber is used, k(Q,Q0) for JSMP12 appears to be consistent within the estimated uncertainty range of (k(Q,Q0)field.
外照射放疗中吸收剂量到水的标准剂量学中射束质转换因子(k(Q,Q0))的不确定度,是通过将为每种电离室计算的每个射束质转换因子的不确定度进行合成来确定的。然而,无法保证同一类型的电离室具有相同的结构和厚度,所以可能存在个体差异。我们在考虑电离室个体差异及临床辐射野的情况下,使用电离室剂量仪和直线加速器,在没有特定装置或技术的情况下评估了JSMP12中k(Q,Q0)的不确定度。对交叉校准公式进行了修正,并使用修正后的公式确定了实验值的射束质转换因子[(k(Q,Q0))field]。计算得出其不确定度为1.9%。对于6兆伏和10兆伏光子束,实验值的(k(Q,Q0))field与日本医学物理学会12(JSMP12)的k(Q,Q0)之间的差异分别为0.73%和0.88%,均在±1.9%以内。这表明在估计的不确定度范围内,JSMP12的k(Q,Q0)与实验值的(k(Q,Q0))field一致。尽管即使使用同一类型的电离室也可能产生个体间差异,但在(k(Q,Q0)field的估计不确定度范围内,JSMP12的k(Q,Q0)似乎是一致的。