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不同营养状况的农村人群中的糖尿病以及这一令人担忧的情况需要更多地关注其与营养不良的关联。

Diabetes in rural individuals of different nutritional status and the alarming situation demands focus more on its under-nutrition association.

作者信息

Maiti Smarajit, Sinha Nirmalya K, Khan Md Mobidullah, Das Prasanta K, Chattopadhyay Jadab C

机构信息

Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory, Oriental Institute of Science and Technology , Midnapore, West Bengal , India .

出版信息

Arch Physiol Biochem. 2015 Feb;121(1):26-31. doi: 10.3109/13813455.2014.959973. Epub 2014 Sep 22.

Abstract

OBJECTIVE

To study the relationship of nutritional-status with diabetes.

DESIGN

The socioeconomics/anthropometrics, blood-glucose/systemic-hypertension are evaluated in consecutively-selected diabetic-patients.

SETTING

Semi-urban/rural India.

SUBJECTS

Hyperglycaemic patients (total 90/male 37).

RESULTS

Blood-glucose (PP-mean ± SE) in individuals is overweight - 38.89% (226.94 ± 9.59), normal-weight - 50% (217.58 ± 1.34), underweight - 11.11% (305.50 ± 21.35) indicating most hyperglycaemia in undernourished-group (F = 6.357, p < 0.003). This group occupies higher glucose-groups in ≤140, 141-270, and ≥270 mg/dL. The blood-glucose negatively correlates with waist(r = -0.282; p < 0.01) and hip (r = -0.254; p < 0.05) circumference indicating the under-nutrition association with glucose-homeostasis (F = 7.6-8.2, p < 0.001). The higher glucose is noticed in more number of individuals in lower (<40 years) age-group (χ(2 )= 12.86; p < 0.002/ρ = -0.355; p < 0.001). The prevalence of hypertension is 28% (underweight = 20%, overweight = 27%, normal = 30%). The group of 141-270 mg/dL glucose has 45% and rest groups together have 23% hypertensive individuals relating directly, hypertension and diabetic-onset.

CONCLUSIONS

Diabetes, explored in <40 years group and even more in female should be extensively studied accounting WHO categorization (1985/TRS/727) of malnutrition related diabetes (MRDM). Further, different interactive risk-factors should be properly addressed and the global-malnutrition/gender-based inequities be eradicated.

摘要

目的

研究营养状况与糖尿病之间的关系。

设计

对连续选取的糖尿病患者进行社会经济学/人体测量学、血糖/全身性高血压评估。

地点

印度半城市/农村地区。

研究对象

高血糖患者(共90例/男性37例)。

结果

超重个体的血糖(餐后平均值±标准误)为38.89%(226.94±9.59),正常体重个体为50%(217.58±1.34),体重过轻个体为11.11%(305.50±21.35),表明营养不良组高血糖情况最为严重(F = 6.357,p < 0.003)。该组在血糖≤140、141 - 270以及≥270mg/dL的分组中占比更高。血糖与腰围(r = -0.282;p < 0.01)和臀围(r = -0.254;p < 0.05)呈负相关,表明营养不良与葡萄糖稳态有关(F = 7.6 - 8.2,p < 0.001)。在年龄较低(<40岁)的人群中,血糖较高的个体数量更多(χ² = 12.86;p < 0.002/ρ = -0.355;p < 0.001)。高血压患病率为28%(体重过轻 = 20%,超重 = 27%,正常 = 30%)。血糖在141 - 270mg/dL组中45%的个体患有高血压,其余组中共有23%的个体患有高血压,这直接关联到高血压与糖尿病发病。

结论

根据世界卫生组织(1985/TRS/727)对营养不良相关糖尿病(MRDM)的分类,对于40岁以下人群尤其是女性中发现的糖尿病应进行广泛研究。此外,应妥善处理不同的交互风险因素,消除全球营养不良/基于性别的不平等现象。

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