Maiti Smarajit, Sinha Nirmalya K, Khan Md Mobidullah, Das Prasanta K, Chattopadhyay Jadab C
Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory, Oriental Institute of Science and Technology , Midnapore, West Bengal , India .
Arch Physiol Biochem. 2015 Feb;121(1):26-31. doi: 10.3109/13813455.2014.959973. Epub 2014 Sep 22.
To study the relationship of nutritional-status with diabetes.
The socioeconomics/anthropometrics, blood-glucose/systemic-hypertension are evaluated in consecutively-selected diabetic-patients.
Semi-urban/rural India.
Hyperglycaemic patients (total 90/male 37).
Blood-glucose (PP-mean ± SE) in individuals is overweight - 38.89% (226.94 ± 9.59), normal-weight - 50% (217.58 ± 1.34), underweight - 11.11% (305.50 ± 21.35) indicating most hyperglycaemia in undernourished-group (F = 6.357, p < 0.003). This group occupies higher glucose-groups in ≤140, 141-270, and ≥270 mg/dL. The blood-glucose negatively correlates with waist(r = -0.282; p < 0.01) and hip (r = -0.254; p < 0.05) circumference indicating the under-nutrition association with glucose-homeostasis (F = 7.6-8.2, p < 0.001). The higher glucose is noticed in more number of individuals in lower (<40 years) age-group (χ(2 )= 12.86; p < 0.002/ρ = -0.355; p < 0.001). The prevalence of hypertension is 28% (underweight = 20%, overweight = 27%, normal = 30%). The group of 141-270 mg/dL glucose has 45% and rest groups together have 23% hypertensive individuals relating directly, hypertension and diabetic-onset.
Diabetes, explored in <40 years group and even more in female should be extensively studied accounting WHO categorization (1985/TRS/727) of malnutrition related diabetes (MRDM). Further, different interactive risk-factors should be properly addressed and the global-malnutrition/gender-based inequities be eradicated.
研究营养状况与糖尿病之间的关系。
对连续选取的糖尿病患者进行社会经济学/人体测量学、血糖/全身性高血压评估。
印度半城市/农村地区。
高血糖患者(共90例/男性37例)。
超重个体的血糖(餐后平均值±标准误)为38.89%(226.94±9.59),正常体重个体为50%(217.58±1.34),体重过轻个体为11.11%(305.50±21.35),表明营养不良组高血糖情况最为严重(F = 6.357,p < 0.003)。该组在血糖≤140、141 - 270以及≥270mg/dL的分组中占比更高。血糖与腰围(r = -0.282;p < 0.01)和臀围(r = -0.254;p < 0.05)呈负相关,表明营养不良与葡萄糖稳态有关(F = 7.6 - 8.2,p < 0.001)。在年龄较低(<40岁)的人群中,血糖较高的个体数量更多(χ² = 12.86;p < 0.002/ρ = -0.355;p < 0.001)。高血压患病率为28%(体重过轻 = 20%,超重 = 27%,正常 = 30%)。血糖在141 - 270mg/dL组中45%的个体患有高血压,其余组中共有23%的个体患有高血压,这直接关联到高血压与糖尿病发病。
根据世界卫生组织(1985/TRS/727)对营养不良相关糖尿病(MRDM)的分类,对于40岁以下人群尤其是女性中发现的糖尿病应进行广泛研究。此外,应妥善处理不同的交互风险因素,消除全球营养不良/基于性别的不平等现象。