在一个与印度不动杆菌密切相关的人类临床分离株中发现了碳青霉烯类耐药性。
Carbapenem resistance in a human clinical isolate identified to be closely related to Acinetobacter indicus.
机构信息
INSERM U914 'Emerging Resistance to Antibiotics', K.-Bicêtre, France.
INSERM U914 'Emerging Resistance to Antibiotics', K.-Bicêtre, France; Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Fribourg, Switzerland.
出版信息
Int J Antimicrob Agents. 2014 Oct;44(4):345-50. doi: 10.1016/j.ijantimicag.2014.05.022. Epub 2014 Jul 19.
Here we report a case of carbapenem resistance in a human clinical isolate that was found to be closely related to the newly described environmental species Acinetobacter indicus. This strain harboured the blaOXA-23 carbapenemase gene located on a conjugative plasmid. Partial sequencing of 16S rDNA and rpoB genes, together with matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) analysis, showed that this strain was distantly related to the Acinetobacter baumannii-calcoaceticus complex and was closely related to A. indicus.
我们在此报告了一例人类临床分离株的碳青霉烯类耐药性，该分离株与新描述的环境种嗜麦芽寡养单胞菌密切相关。该菌株携带 blaOXA-23 碳青霉烯酶基因，位于可接合质粒上。16S rDNA 和 rpoB 基因的部分测序以及基质辅助激光解吸/电离飞行时间（MALDI-TOF）分析表明，该菌株与鲍曼不动杆菌-醋酸钙不动杆菌复合体亲缘关系较远，与嗜麦芽寡养单胞菌密切相关。
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