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一项关于前列腺手术患者感染性并发症的韩国前瞻性多中心研究:危险因素及抗生素预防的疗效。

A prospective Korean multicenter study for infectious complications in patients undergoing prostate surgery: risk factors and efficacy of antibiotic prophylaxis.

作者信息

Hwang Eu Chang, Jung Seung Il, Kwon Dong Deuk, Lee Gilho, Bae Jae Hyun, Na Yong Gil, Min Seung Ki, Son Hwancheol, Lee Sun Ju, Chung Jae Min, Chung Hong, Cho In Rae, Kim Young Ho, Kim Tae-Hyoung, Chang In Ho

机构信息

Department of Urology, Chonnam National University, Hwasun, Korea. ; The Korean Association of Urogenital Tract Infection and Inflammation (KAUTII), Seoul, Korea.

Department of Urology, Dankook University, College of Medicine, Cheonan, Korea. ; The Korean Association of Urogenital Tract Infection and Inflammation (KAUTII), Seoul, Korea.

出版信息

J Korean Med Sci. 2014 Sep;29(9):1271-7. doi: 10.3346/jkms.2014.29.9.1271. Epub 2014 Sep 2.

DOI:10.3346/jkms.2014.29.9.1271
PMID:25246747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4168182/
Abstract

This multicenter study was undertaken to determine the efficacy of antibiotic prophylaxis and identify the risk factors for infectious complications after prostate surgery in Korean patients. A total of 424 patients who underwent surgery of the prostate were reviewed. All patients underwent urinalysis and urine culture preoperatively and postoperatively. Efficacy of antibiotic prophylaxis and risk factors for infectious complications were investigated. Infectious complications were observed in 34.9% of all patients. Factors independently associated with infectious complications were diabetes mellitus (adjusted OR, 1.99; 95% CI, 1.09-3.65, P=0.025) and operation time (adjusted OR, 1.08; 95% CI, 1.03-1.13, P=0.004). Clinicians should be aware of the high risk of infectious complications in patients with diabetes and those who undergo a prolonged operation time. Neither the type nor duration of prophylactic antibiotics resulted in differences in infectious complications.

摘要

本多中心研究旨在确定抗生素预防的疗效,并识别韩国患者前列腺手术后感染并发症的危险因素。共回顾了424例接受前列腺手术的患者。所有患者在术前和术后均进行了尿液分析和尿培养。研究了抗生素预防的疗效和感染并发症的危险因素。所有患者中34.9%观察到感染并发症。与感染并发症独立相关的因素为糖尿病(校正比值比,1.99;95%置信区间,1.09 - 3.65,P = 0.025)和手术时间(校正比值比,1.08;95%置信区间,1.03 - 1.13,P = 0.004)。临床医生应意识到糖尿病患者和手术时间延长患者发生感染并发症的高风险。预防性抗生素的类型和持续时间均未导致感染并发症出现差异。

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