Varma Devesh K, Belovay Graham W, Tam Diamond Y, Ahmed Iqbal Ike K
From the University of Toronto (Varma, Belovay, Tam, Ahmed), Toronto, Trillium Health Partners (Varma, Ahmed), and Credit Valley EyeCare (Varma, Tam, Ahmed), Mississauga, Ontario, Canada.
From the University of Toronto (Varma, Belovay, Tam, Ahmed), Toronto, Trillium Health Partners (Varma, Ahmed), and Credit Valley EyeCare (Varma, Tam, Ahmed), Mississauga, Ontario, Canada.
J Cataract Refract Surg. 2014 Nov;40(11):1843-9. doi: 10.1016/j.jcrs.2014.02.045. Epub 2014 Sep 22.
To report a series of eyes that developed malignant glaucoma after cataract surgery.
Private academic practice, Toronto, Ontario, Canada.
Retrospective case series.
Eyes that developed malignant glaucoma after cataract surgery were treated with medical therapy. This was followed by laser iridozonulohyaloidotomy, anterior chamber reformation and intraocular lens (IOL) pushback, and finally with surgical iridozonulohyaloidovitrectomy if all other measures were unsuccessful. Refraction, intraocular pressure (IOP), gonioscopy, and anterior chamber depth (ACD) by anterior segment optical coherence tomography were analyzed before treatment and after treatment.
The study evaluated 20 eyes of 18 female patients aged 44 to 86 years. Preoperatively, the mean refraction was +3.11 diopters (D) ± 2.89 (SD), the mean axial length was 21.30 ± 1.40 mm, and all eyes had narrow or closed angles. Malignant glaucoma was diagnosed a mean of 5.8 ± 7.1 weeks postoperatively. At diagnosis, the mean refraction was -2.15 ± 2.95 D; the mean ACD, 2.49 ± 0.72 mm; and the mean IOP, 28.3 ± 10.8 mm Hg on a mean of 1.3 ± 1.6 medications. Two eyes responded to cycloplegia, 7 to laser iridozonulohyaloidotomy, and 6 to anterior chamber reformation-IOL pushback; 5 eyes required vitrectomy. Posttreatment, the mean refraction was -0.56 ± 1.07 D; the mean ACD, 3.30 ± 0.50 mm; and the mean IOP, 14.4 ± 4.60 mm Hg on a mean of 1.2 ± 1.4 medications. Cycloplegia was discontinued in 17 eyes.
Malignant glaucoma can occur after phacoemulsification and presents with myopic surprise, anterior chamber shallowing and, possibly, elevated IOP.
No author has a financial or proprietary interest in any material or method mentioned.
报告一系列白内障手术后发生恶性青光眼的病例。
加拿大安大略省多伦多市的私人学术诊所。
回顾性病例系列研究。
对白内障手术后发生恶性青光眼的患者采用药物治疗。随后进行激光虹膜周切术、前房重建和人工晶状体(IOL)复位,如果所有其他措施均无效,则最终进行手术虹膜周切玻璃体切除术。在治疗前和治疗后分析屈光、眼压(IOP)、前房角镜检查以及前段光学相干断层扫描测量的前房深度(ACD)。
该研究评估了18例年龄在44至86岁之间女性患者的20只眼。术前,平均屈光为+3.11屈光度(D)±2.89(标准差),平均眼轴长度为21.30±1.40mm,所有眼睛均为窄角或闭角。恶性青光眼平均在术后5.8±7.1周被诊断出来。诊断时,平均屈光为-2.15±2.95D;平均ACD为2.49±0.72mm;平均IOP为28.3±10.8mmHg,平均使用1.3±1.6种药物。2只眼对睫状肌麻痹有反应,7只眼对激光虹膜周切术有反应,6只眼对前房重建-IOL复位有反应;5只眼需要玻璃体切除术。治疗后,平均屈光为-0.56±1.07D;平均ACD为3.30±0.50mm;平均IOP为14.4±4.60mmHg,平均使用1.2±1.4种药物。17只眼中停用了睫状肌麻痹剂。
恶性青光眼可发生于超声乳化术后,表现为近视性意外、前房变浅,可能还有眼压升高。
没有作者对文中提及的任何材料或方法有财务或专利权益。