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超声乳化白内障吸除术联合人工晶状体植入治疗并发性青光眼的长期疗效观察。

Long-term therapeutic efficacy of phacoemulsification with intraocular lens implantation in patients with phacomorphic glaucoma.

机构信息

Department of Ophthalmology, Maryknoll Hospital, College of Medicine, Inje University, Busan, Korea.

出版信息

J Cataract Refract Surg. 2010 May;36(5):783-9. doi: 10.1016/j.jcrs.2009.11.023.

DOI:10.1016/j.jcrs.2009.11.023
PMID:20457370
Abstract

PURPOSE

To evaluate the long-term therapeutic efficacy of phacoemulsification with intraocular lens (IOL) implantation in treating phacomorphic glaucoma.

SETTING

Ophthalmology Department, Maryknoll Hospital, Busan, Korea.

METHODS

This study evaluated eyes that had phacoemulsification with IOL implantation to treat phacomorphic glaucoma. Intraocular pressure (IOP), corrected distance visual acuity (CDVA), and anterior chamber depth (ACD) were measured preoperatively and postoperatively. The minimum follow-up was 48 months.

RESULTS

The mean IOP in the 26 eyes was 49.0 mm Hg +/- 10.4 (SD) (range 31 to 70 mm Hg) preoperatively and 13.2 +/- 2.8 mm Hg (range 8 to 20 mm Hg) 48 months postoperatively (P<.0001, paired t test). No eye had increased IOP over the follow-up. The postoperative IOP was significantly lower 1 day postoperatively (P<.000, paired t test). The improvement in CDVA was statistically significant from 1 week postoperatively (P<.0001, paired t test). The CDVA improved postoperatively except in 1 eye with a preoperative acuity of no light perception. The CDVA was 20/50 or better in 16 eyes (61.5%). Preoperatively, the ACD was shallow (mean 1.5 +/- 0.3 mm) because of the swollen lens; the mean postoperative ACD was 2.6 +/- 0.1 mm; the increase was statistically significant. The mean preoperative ratio of lens thickness to axial length was 0.25 +/- 0.01, indicating a shallow ACD. In 1 eye, peripheral anterior synechias were seen on gonioscopy immediately after surgery; the eye required continuous postoperative medication for IOP control.

CONCLUSION

Phacoemulsification with IOL implantation was effective in treating phacomorphic glaucoma.

摘要

目的

评估超声乳化白内障吸除联合人工晶状体(IOL)植入术治疗并发性白内障青光眼的长期疗效。

地点

韩国釜山玛利诺医院眼科。

方法

本研究评估了接受超声乳化白内障吸除联合人工晶状体植入术治疗并发性白内障青光眼的患者。术前和术后分别测量眼压(IOP)、矫正远视力(CDVA)和前房深度(ACD)。随访时间至少为 48 个月。

结果

26 只眼的平均眼压术前为 49.0 mm Hg +/- 10.4(SD)(范围 31 至 70 mm Hg),术后 48 个月为 13.2 +/- 2.8 mm Hg(范围 8 至 20 mm Hg)(P<.0001,配对 t 检验)。随访期间无眼压升高的眼。术后第 1 天眼压显著降低(P<.000,配对 t 检验)。术后 CDVA 明显改善,术后 1 周时差异有统计学意义(P<.0001,配对 t 检验)。除术前无光感的 1 只眼外,其余眼术后视力均提高。术后 16 只眼(61.5%)视力达到 20/50 或以上。术前由于晶状体肿胀,ACD 较浅(平均 1.5 +/- 0.3 mm);术后平均 ACD 为 2.6 +/- 0.1 mm,差异有统计学意义。术前晶状体厚度与眼轴长度的比值平均为 0.25 +/- 0.01,提示 ACD 较浅。术后 1 只眼出现周边前粘连,立即行房角镜检查;该眼需要持续术后药物治疗以控制眼压。

结论

超声乳化白内障吸除联合人工晶状体植入术治疗并发性白内障青光眼有效。

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