Division of Clinical Epidemiology and Evaluative Sciences Research, Center for Integrative Medicine, Weill Cornell Medical College, 338 East 66th Street, New York, NY, 10065, USA.
BMC Complement Altern Med. 2014 Sep 23;14:349. doi: 10.1186/1472-6882-14-349.
Among underserved, largely minority women who were breast cancer survivors, this pilot project was designed to evaluate the quality of life outcomes of a 20 week Contemplative Self-Healing Program.
Women previously treated for stage I-III breast cancer were assessed before and after the 20 week program with the FACT-G, FACT-B, FACIT-Spirituality, ECOG, and the Impact of Events Scale. They participated in a 20-week intervention involving guided meditation and cognitive-affective-behavioral learning.
With an average age of 63, 62% of the participants were African-American or Latino. With an average of 5.4 years since the diagnosis of breast cancer, 72% had an ECOG performance status of 1. 57% were currently working. Their baseline FACT-G was 80.5 ± 15.1, and their baseline Impact of Events Scale was 26.3 ± 18.9. The within-patient improvement on the FACT-G was 4.6 ± 10.9 (p = .01); in parallel the FACT-B improved by 2.8 ± 12.8 points (p = .03). The Impact of Events Scale improved by 6.6 ± 15.5 points (p = .01). There was significant within-patient improvement on both the avoidance scale (3.8 ± 9.2) and on the intrusion scale (2.9 ± 7.9). Patients who attended more sessions and conducted more home practice had greater improvements in quality of life.
Persons receiving a 20-session contemplative self healing intervention showed improved quality of life, with a clinically and statistically significant increase in the FACT-G. In addition, this population showed a significant reduction in post-traumatic stress symptoms assessed by the Impact of Events Scale.
Clinical Trials Gov NCT00278837.
在服务不足的、主要是少数族裔的乳腺癌幸存者中,本试点项目旨在评估 20 周沉思自我疗愈计划的生活质量结果。
在接受 20 周的方案治疗前后,对之前接受过 I-III 期乳腺癌治疗的女性使用 FACT-G、FACT-B、FACIT-精神、ECOG 和事件影响量表进行评估。她们参加了一项为期 20 周的干预措施,包括引导冥想和认知情感行为学习。
参与者的平均年龄为 63 岁,其中 62%为非裔美国人或拉丁裔。在诊断出乳腺癌后的平均时间为 5.4 年,72%的患者 ECOG 表现状态为 1。57%的人目前正在工作。她们的基线 FACT-G 为 80.5 ± 15.1,基线事件影响量表为 26.3 ± 18.9。FACT-G 患者的个体内改善为 4.6 ± 10.9(p =.01);同时,FACT-B 改善了 2.8 ± 12.8 分(p =.03)。事件影响量表改善了 6.6 ± 15.5 分(p =.01)。回避量表(3.8 ± 9.2)和入侵量表(2.9 ± 7.9)的个体内改善均具有统计学意义。参加更多疗程和进行更多家庭实践的患者生活质量改善更大。
接受 20 次沉思自我疗愈干预的患者生活质量得到改善,FACT-G 有临床和统计学意义上的显著提高。此外,该人群的事件影响量表评估的创伤后应激症状显著减少。
ClinicalTrials.gov NCT00278837。