Jandaghi Ali Babaei, Amanian Dayan, Roudbari Seyed Ali, Kanafi Alireza Rajabzadeh, Pourghorban Ramin
Department of Radiology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran ; Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Department of Radiology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Pol J Radiol. 2014 Sep 19;79:323-7. doi: 10.12659/PJR.890690. eCollection 2014.
The purpose of this study was to compare patients with multiple sclerosis and healthy control subjects as regards hemodynamics of cerebral venous drainage.
MATERIAL/METHODS: Between December 2012 and May 2013, 44 consecutive patients with multiple sclerosis and 44 age- and sex-matched healthy subjects underwent the B-mode, color Doppler, and duplex Doppler evaluations of the internal jugular vein (IJV) and vertebral vein. The following four parameters were investigated: IJV stenosis, reversal of postural control of the cerebral venous outflow pathways, absence of detectable blood flow in the IJVs and/or vertebral veins, and reflux in the IJVs and/or vertebral veins in the sitting or supine position.
In the study group, IJV stenosis, postural control reversal of the cerebral venous outflow pathways, and absence of flow in the IJVs and/or vertebral veins were found in 3 (6.8%), 2 (4.5%), and 3 (6.8%) patients, respectively. In the control group, IJV stenosis (P=0.12), postural control reversal of the cerebral venous outflow pathways (P=0.50), and absence of flow (P=0.12) were not detected. Abnormal reflux was found neither in multiple sclerosis patients nor in healthy subjects.
No significant difference in the cerebral venous drainage through the IJV or vertebral vein was found between patients with multiple sclerosis and healthy subjects within any of the investigated ultrasonographic parameters.
本研究旨在比较多发性硬化症患者与健康对照者在脑静脉引流血液动力学方面的差异。
材料/方法：2012年12月至2013年5月期间，44例连续性多发性硬化症患者和44例年龄及性别匹配的健康受试者接受了颈内静脉（IJV）和椎动脉的B型、彩色多普勒及双功多普勒评估。研究了以下四个参数：IJV狭窄、脑静脉流出途径的姿势控制逆转、IJV和/或椎动脉中未检测到血流以及IJV和/或椎动脉在坐位或仰卧位时的反流。
在研究组中，分别有3例（6.8%）、2例（4.5%）和3例（6.8%）患者出现IJV狭窄、脑静脉流出途径的姿势控制逆转以及IJV和/或椎动脉无血流。在对照组中，未检测到IJV狭窄（P=0.12）、脑静脉流出途径的姿势控制逆转（P=0.50）和无血流（P=0.12）。在多发性硬化症患者和健康受试者中均未发现异常反流。
在任何所研究的超声参数方面，多发性硬化症患者与健康受试者之间通过IJV或椎动脉的脑静脉引流均未发现显著差异。
