Abedelahi Ali, Rezaei-Tavirani Mostafa, Mohammadnejad Daryosh
Dept. of Anatomical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran J Cancer Prev. 2013 Summer;6(3):123-32.
Ovarian tissue freezing or cryopreservation might be the only acceptable method for preserving the young women fertility, before radiotherapy or chemotherapy. This technology might be used for patients with recurrent ovarian cysts or endometriosis, without ovarian stimulation. Many efforts have made to improve cryopreservation conditions that should be seriously considered for cancer patients. Vitrification is a process which prevents ovarian tissue from cryo damage, then preserves cell viability. Both methods have used for evaluating not only the follicular development, but also the fertility after freezing and thawing. In this manuscript, we have discussed the techniques of ovarian tissue vitrification, then graft and maturation or follicular development is also mentioned.
在进行放疗或化疗之前，卵巢组织冷冻或低温保存可能是保存年轻女性生育能力的唯一可接受方法。这项技术可用于患有复发性卵巢囊肿或子宫内膜异位症的患者，无需进行卵巢刺激。人们已做出许多努力来改善冷冻保存条件，这对于癌症患者而言应予以认真考虑。玻璃化是一种防止卵巢组织受到冷冻损伤从而保存细胞活力的过程。这两种方法都已用于评估卵泡发育情况以及冷冻和解冻后的生育能力。在本手稿中，我们讨论了卵巢组织玻璃化技术，还提及了移植以及成熟或卵泡发育情况。
