Hasanzadeh Malihe, Zamiri-Akhlaghi Amir, Hassanpoor-Moghaddam Maryam, Shahidsales Soodabeh
Women Health Research center, Dept. of Gynecology Oncology, Mashhad University of Medical Sciences, Mashhad, Iran.
Dept. of Gynecology Oncology, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Iran J Cancer Prev. 2014 Summer;7(3):175-8.
Invasive squamous cell carcinoma of the vulva is primarily a disease of postmenopausal women and thus is rarely associated with pregnancy.
We have reported on a young woman under 40 years old with vulvar carcinoma, which occurred during the pregnancy but optimal treatment was delayed to the postpartum period. This 37-year-old woman was diagnosed with 3x3 cm vulvar lesion, 2 weeks after cesarean section, subsequent biopsy revealed squamous cell carcinoma. She had a history of an ulcer on her left labia minor at the third month of the pregnancy. She was treated by a modified radical vulvectomy and bilateral groin lymphadenectomy. She did not receive any additional treatments. Now after two years, she has had no recurrence of the disease.
This case emphasizes on the need to consider malignancy as a differential diagnosis in vulvar lesions of pregnant young women.
外阴浸润性鳞状细胞癌主要是绝经后女性的疾病，因此很少与妊娠相关。
我们报道了一名40岁以下的年轻女性患有外阴癌，该疾病发生在妊娠期间，但最佳治疗推迟到产后。这名37岁的女性在剖宫产术后2周被诊断出有3×3 cm的外阴病变，随后的活检显示为鳞状细胞癌。她在妊娠第三个月时左侧小阴唇有溃疡病史。她接受了改良根治性外阴切除术和双侧腹股沟淋巴结清扫术。她没有接受任何其他治疗。现在两年过去了，她没有疾病复发。
该病例强调了在年轻孕妇外阴病变中需要将恶性肿瘤作为鉴别诊断的必要性。
