Woźnica Magdalena, Chaoui Nicolas, Taabache Soraya, Blechert Siegfried
Institute of Chemistry, Technical University Berlin, Strasse des 17. Juni 135, 10623 Berlin (Germany), Fax: +49 30 314 29745.
Chemistry. 2014 Nov 3;20(45):14624-8. doi: 10.1002/chem.201404440. Epub 2014 Sep 24.
Mesoporous graphitic carbon nitride (mpg-C3 N4 ) was found to be an efficient heterogeneous photocatalyst for the metal-free radical cyclization of 2-bromo-1,3-dicarbonyl compounds. Reactions leading to functionalized cyclopentanes proceed under mild conditions and can be conducted in a continuous flow photoreactor. Compared to the batch reaction, the use of a continuous flow reactor resulted in a significant reduction in reaction time (complete conversion of 0.04 mmol of substrate in a batch was achieved after 4 h, whereas in a flow reactor the same amount of substrate was fully converted into a product within 40 min). Mechanistic studies of the reaction showed that THF plays not only the role of solvent, but is also a crucial hydrogen and electron donor.
介孔石墨相氮化碳（mpg-C3N4）被发现是一种用于2-溴-1,3-二羰基化合物无金属自由基环化反应的高效多相光催化剂。生成官能化环戊烷的反应在温和条件下进行，并且可以在连续流光反应器中进行。与间歇反应相比，使用连续流光反应器可显著缩短反应时间（间歇反应中0.04 mmol底物在4小时后实现完全转化，而在流光反应器中相同量的底物在40分钟内完全转化为产物）。该反应的机理研究表明，四氢呋喃不仅起到溶剂的作用，还是关键的氢和电子供体。
