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面瘫作为急性髓系白血病的一种不寻常的首发症状。

Facial palsy as an unusual presenting symptom associated with acute myeloid leukemia.

作者信息

Kubota Kazuo, Ozeki Michio, Hori Tomohiro, Kanda Kaori, Funato Michinori, Asano Takahiko, Fukao Toshiyuki, Kondo Naomi

机构信息

Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.

出版信息

Pediatr Int. 2014 Aug;56(4):e37-40. doi: 10.1111/ped.12384.

Abstract

Extramedullary infiltration is common in acute myeloid leukemia (AML) patients. Although AML can cause neurological symptoms, especially when associated with extramedullary infiltration, a presenting manifestation of facial palsy is rare. We report on a 1-year-old boy who developed right facial palsy. Detailed examination led to a diagnosis of AML (French-American-British classification M1). Magnetic resonance imaging enhanced with gadolinium-diethylenetriamine penta-acetic acid showed abnormal enhancement of the right facial nerve, which disappeared after chemotherapy. AML should be considered as a differential diagnosis of facial palsy. Enhanced magnetic resonance imaging may be useful for diagnosing facial palsy associated with AML and for evaluating treatment outcome.

摘要

髓外浸润在急性髓系白血病(AML)患者中很常见。虽然AML可引起神经症状,尤其是与髓外浸润相关时,但以面神经麻痹为首发表现较为罕见。我们报告了一名1岁男孩,他出现了右侧面神经麻痹。详细检查后诊断为AML(法美英分类M1型)。钆喷酸葡胺增强磁共振成像显示右侧面神经异常强化,化疗后消失。AML应被视为面神经麻痹的鉴别诊断之一。增强磁共振成像可能有助于诊断与AML相关的面神经麻痹并评估治疗效果。

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