Camsarı Ulas, Viguera Adele C, Ralston Laurel, Baldessarini Ross J, Cohen Lee S
Department of Psychiatry, Mayo Clinic College of Medicine, Rochester, MN, USA.
Arch Womens Ment Health. 2014 Dec;17(6):583-6. doi: 10.1007/s00737-014-0465-0. Epub 2014 Sep 25.
To characterize current treatment practices, we compared the use of atypical antipsychotic drugs among women of childbearing age to men based on electronic medical records of 1073 hospital-based psychiatric outpatients given at least one second-generation antipsychotic drug. One quarter of psychiatric outpatients sampled were prescribed at least one atypical antipsychotic, in more than half of cases for off-label indications. Women were significantly more likely than men to be diagnosed with mood or anxiety disorders than psychotic disorders and to be prescribed quetiapine (60.7 vs. 48.0 %) or aripiprazole (31.2 vs. 23.9 %), but less likely risperidone (15.8 vs. 26.1 %) or ziprasidone (10 vs. 14 %).
为了描述当前的治疗方法，我们基于1073名接受过至少一种第二代抗精神病药物治疗的住院精神科门诊患者的电子病历，比较了育龄女性和男性使用非典型抗精神病药物的情况。抽样的精神科门诊患者中有四分之一至少被开了一种非典型抗精神病药物，超过半数的情况是用于非适应证。女性被诊断为心境或焦虑障碍而非精神障碍的可能性显著高于男性，且女性比男性更有可能被开喹硫平（60.7%对48.0%）或阿立哌唑（31.2%对23.9%），但被开利培酮（15.8%对26.1%）或齐拉西酮（10%对14%）的可能性较小。
