越南北部省份的恙虫病：一家国家级转诊医院入院情况的观察性研究
Scrub typhus in the northern provinces of Vietnam: an observational study of admissions to a national referral hospital.
作者信息
Nadjm Behzad, Thuy Pham T, Trang Van D, Ha Le Dang, Kinh Nguyen V, Wertheim Heiman F
机构信息
Oxford University Clinical Research Unit, Hanoi, Vietnam
Bach Mai Hospital, Hanoi, Vietnam.
出版信息
Trans R Soc Trop Med Hyg. 2014 Nov;108(11):739-40. doi: 10.1093/trstmh/tru145. Epub 2014 Sep 23.
BACKGROUND
Scrub typhus is a common cause of fever in parts of South East and Southern Asia. Little is known about the disease burden in Vietnam.
METHODS
A 2-year observational study of scrub typhus at a tertiary referral hospital in northern Vietnam was carried out. Diagnosis was based on a single serological test in patients with suggestive clinical symptoms.
RESULTS
Scrub typhus was diagnosed in 3.5% (251/7226) of admissions. Cases occurred throughout the year, with incidence highest in the summer. Although complications were common, mortality was low (1.2%; 3/251).
CONCLUSIONS
These data suggest that scrub typhus is common, with a seasonal distribution in northern Vietnam.
背景
恙虫病是东南亚和南亚部分地区发热的常见病因。越南的疾病负担情况鲜为人知。
方法
在越南北部一家三级转诊医院对恙虫病进行了为期2年的观察性研究。诊断基于有提示性临床症状患者的单次血清学检测。
结果
入院患者中3.5%（251/7226）被诊断为恙虫病。病例全年均有发生，夏季发病率最高。尽管并发症常见，但死亡率较低（1.2%；3/251）。
结论
这些数据表明恙虫病在越南北部很常见，且呈季节性分布。
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