Hovik Kjell Tore, Egeland Jens, Isquith Peter K, Gioia Gerard, Skogli Erik Winther, Andersen Per Normann, Øie Merete
1 Innlandet Hospital Trust, Lillehammer, Norway.
2 University of Oslo, Norway.
J Atten Disord. 2017 Aug;21(10):811-823. doi: 10.1177/1087054714550336. Epub 2014 Sep 24.
The aim is to investigate the everyday executive function (EF) in children with Tourette syndrome (TS), Inattentive or Combined presentations of ADHD (ADHD-I/ADHD-C), autism spectrum disorders (ASD), and typically developing children (TDC).
Nineteen TS, 33 ADHD-C, 43 ADHD-I, 34 ASD, and 50 TDC participated (8-17 years). Parents completed the Behavior Rating Inventory of Executive Function (BRIEF).
TS, ADHD-C, ADHD-I, or ASD were rated with significantly more regulation problems on all scales compared with TDC. Considerable overlap of symptoms between clinical groups made differentiation difficult on individual scales. Scale configurations showed children with TS to have more problems with emotional control (EC) than cognitive flexibility in relation to children with ASD, more problems with EC than inhibitory control in relation to ADHD-C, and more problems with EC than planning/organizing in relation to ADHD-I.
Paired BRIEF scales dissociated EF problems in children with TS from children with ADHD-C, ADHD-I, or ASD. Clinical relevance is discussed.
旨在研究抽动秽语综合征（TS）、注意力不集中型或混合型注意力缺陷多动障碍（ADHD-I/ADHD-C）、自闭症谱系障碍（ASD）患儿以及正常发育儿童（TDC）的日常执行功能（EF）。
19名TS患儿、33名ADHD-C患儿、43名ADHD-I患儿、34名ASD患儿以及50名TDC儿童（年龄8 - 17岁）参与研究。家长完成执行功能行为评定量表（BRIEF）。
与TDC相比，TS、ADHD-C、ADHD-I或ASD在所有量表上的调节问题评分均显著更高。临床组之间症状的大量重叠使得在单个量表上进行区分变得困难。量表配置显示，与ASD患儿相比，TS患儿在情绪控制（EC）方面比认知灵活性存在更多问题；与ADHD-C患儿相比，TS患儿在EC方面比抑制控制存在更多问题；与ADHD-I患儿相比，TS患儿在EC方面比计划/组织存在更多问题。
配对的BRIEF量表区分了TS患儿与ADHD-C、ADHD-I或ASD患儿的EF问题。并讨论了其临床相关性。
