巴西犬皮肤弓形虫病中弓形虫的分离及生物学和分子特征分析
Isolation and biological and molecular characterization of Toxoplasma gondii from canine cutaneous toxoplasmosis in Brazil.
作者信息
Pena Hilda F J, Moroz Ludmila R, Sozigan Rita K B, Ajzenberg Daniel, Carvalho Fernando R, Mota Caroline M, Mineo Tiago W P, Marcili Arlei
机构信息
Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil
Departamento de Cirurgia Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
出版信息
J Clin Microbiol. 2014 Dec;52(12):4419-20. doi: 10.1128/JCM.02001-14. Epub 2014 Sep 24.
Abstract
Cutaneous toxoplasmosis is a rare manifestation. This study represents a case report of an immunosuppressed dog that developed nodular dermal lesions caused by Toxoplasma gondii. The isolate (TgDgBr20) was characterized as mouse virulent and was genotyped as type BrI (ToxoDB genotype 6) using PCR-restriction fragment length polymorphism (RFLP) and as Africa 1 through microsatellite analysis.
摘要
皮肤弓形虫病是一种罕见的表现形式。本研究报告了一例免疫抑制犬发生由刚地弓形虫引起的结节性皮肤病变的病例。分离株（TgDgBr20）被鉴定为对小鼠具有致病性，并通过聚合酶链反应-限制性片段长度多态性（PCR-RFLP）分型为BrI型（ToxoDB基因型6），通过微卫星分析分型为非洲1型。
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