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使用多向各向异性符号样本通过LIC映射进行纤维可视化

Fiber Visualization with LIC Maps Using Multidirectional Anisotropic Glyph Samples.

作者信息

Höller Mark, Otto Kay-M, Klose Uwe, Groeschel Samuel, Ehricke Hans-H

机构信息

Institute for Applied Computer Science (IACS), Stralsund University, Zur Schwedenschanze 15, 18435 Stralsund, Germany.

MR Research Group, Department of Diagnostic and Interventional Neuroradiology, University Hospital Tübingen, Hoppe-Seyler-Straße 3, 72076 Tübingen, Germany.

出版信息

Int J Biomed Imaging. 2014;2014:401819. doi: 10.1155/2014/401819. Epub 2014 Aug 28.

DOI:10.1155/2014/401819
PMID:25254038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4164306/
Abstract

Line integral convolution (LIC) is used as a texture-based technique in computer graphics for flow field visualization. In diffusion tensor imaging (DTI), LIC bridges the gap between local approaches, for example directionally encoded fractional anisotropy mapping and techniques analyzing global relationships between brain regions, such as streamline tracking. In this paper an advancement of a previously published multikernel LIC approach for high angular resolution diffusion imaging visualization is proposed: a novel sampling scheme is developed to generate anisotropic glyph samples that can be used as an input pattern to the LIC algorithm. Multicylindrical glyph samples, derived from fiber orientation distribution (FOD) functions, are used, which provide a method for anisotropic packing along integrated fiber lines controlled by a uniform random algorithm. This allows two- and three-dimensional LIC maps to be generated, depicting fiber structures with excellent contrast, even in regions of crossing and branching fibers. Furthermore, a color-coding model for the fused visualization of slices from T1 datasets together with directionally encoded LIC maps is proposed. The methodology is evaluated by a simulation study with a synthetic dataset, representing crossing and bending fibers. In addition, results from in vivo studies with a healthy volunteer and a brain tumor patient are presented to demonstrate the method's practicality.

摘要

线积分卷积(LIC)在计算机图形学中作为一种基于纹理的技术用于流场可视化。在扩散张量成像(DTI)中,LIC弥合了局部方法(例如方向编码分数各向异性映射)与分析脑区之间全局关系的技术(如流线追踪)之间的差距。本文提出了一种先前发表的用于高角分辨率扩散成像可视化的多内核LIC方法的改进:开发了一种新颖的采样方案来生成各向异性的字形样本,这些样本可作为LIC算法的输入模式。使用从纤维取向分布(FOD)函数导出的多圆柱字形样本,它提供了一种沿着由均匀随机算法控制的整合纤维线进行各向异性堆积的方法。这使得能够生成二维和三维LIC图,即使在纤维交叉和分支区域也能以出色的对比度描绘纤维结构。此外,还提出了一种用于将T1数据集的切片与方向编码的LIC图进行融合可视化的颜色编码模型。通过对代表交叉和弯曲纤维的合成数据集进行模拟研究来评估该方法。此外,还展示了对一名健康志愿者和一名脑肿瘤患者进行体内研究的结果,以证明该方法的实用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a810/4164306/3665f66271a2/IJBI2014-401819.015.jpg
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本文引用的文献

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