• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

体外受精和高龄生育带来的新生儿风险。

Neonatal risks from in vitro fertilization and delayed motherhood.

作者信息

Bellieni Carlo Valerio

机构信息

Carlo Valerio Bellieni, Neonatal Intensive Care Unit, University Hospital "Le Scotte", Viale M. Bracci, 53100 Siena, Italy.

出版信息

World J Clin Pediatr. 2012 Dec 8;1(4):34-6. doi: 10.5409/wjcp.v1.i4.34.

DOI:10.5409/wjcp.v1.i4.34
PMID:25254166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4145649/
Abstract

Delayed childbearing (DC) is common in most Western countries. The average age of first-time mothers increased in United States from 21.4 years in 1970 to 25.0 years in 2006 and from 25.4 to 30.8 years in Australia in the same period. It is commonly believed that this has no ominous consequences. But several negative consequences of this behavior are described: stillbirth, prematurity, twins, birth anomalies. Age also decreases women's fertility, thus many couples undergo in vitro fertilization. And we highlight a paradox: medical reproduction techniques decreases their effectiveness with maternal age, but their availability can be an incentive to postpone parenthood. Of course the risks of delayed parenthood involve a minority of cases, but are parents entitled to accept any risk on the behalf of their baby A complete information would make people cautious before deciding to postpone childbearing, though this is often an obliged rather that a free choice: the consumerist society pressure and the difficulty to find an employment have their heavy weight in this choice. But if this choice is not really free, people's interest is to overcome these pressures and to claim for a real broad choice on when becoming parent, despite the pressures made by their cultural environment to postpone parenthood. Moreover, even reproductive techniques have some risks. Unfortunately, mass media often praise and endorse DC, disregarding the increase of premature babies born because of DC, a real alarm for public health. Pediatricians should discourage the culture that makes DC a normal event.

摘要

晚育在大多数西方国家很常见。美国首次生育母亲的平均年龄从1970年的21.4岁增至2006年的25.0岁,同期澳大利亚则从25.4岁增至30.8岁。人们普遍认为这不会带来不良后果。但这种行为存在一些负面后果:死产、早产、双胞胎、出生异常。年龄还会降低女性的生育能力,因此许多夫妇会接受体外受精。我们强调一个矛盾之处:医学生殖技术的效果会随着母亲年龄增长而降低,但其可获得性却可能促使人们推迟生育。当然,晚育的风险只涉及少数情况,但父母有权代表他们的孩子接受任何风险吗?完整的信息会让人们在决定推迟生育前谨慎行事,尽管这往往是一种无奈之举而非自由选择:消费主义社会的压力以及找工作的困难在这个选择中起了很大作用。但如果这个选择并非真正自由,人们的利益在于克服这些压力,并要求在何时成为父母方面有真正广泛的选择,尽管他们的文化环境存在促使推迟生育的压力。此外,即使生殖技术也存在一些风险。不幸的是,大众媒体常常赞扬和认可晚育,而忽视了因晚育导致的早产婴儿数量增加这一公共卫生方面的真正警报。儿科医生应抵制将晚育视为正常现象的文化。

相似文献

1
Neonatal risks from in vitro fertilization and delayed motherhood.体外受精和高龄生育带来的新生儿风险。
World J Clin Pediatr. 2012 Dec 8;1(4):34-6. doi: 10.5409/wjcp.v1.i4.34.
2
Assisted Reproductive Technology Surveillance - 
United States, 2013.辅助生殖技术监测报告——美国,2013 年。
MMWR Surveill Summ. 2015 Dec 4;64(11):1-25. doi: 10.15585/mmwr.ss6411a1.
3
Assisted Reproductive Technology Surveillance — United States, 2012.辅助生殖技术监测—美国,2012 年。
MMWR Surveill Summ. 2015 Aug 14;64(6):1-29.
4
Delayed childbearing.生育推迟。
IPPF Med Bull. 1985 Jun;19(3):3-4.
5
Assisted reproductive technology surveillance--United States, 2011.辅助生殖技术监测——美国,2011 年。
MMWR Surveill Summ. 2014 Nov 21;63(10):1-28.
6
The Best Age for Pregnancy and Undue Pressures.怀孕的最佳年龄与不当压力
J Family Reprod Health. 2016 Sep;10(3):104-107.
7
Desperately seeking parenthood: neonatal nurses reflect on parental anguish.拼命寻求为人父母之路:新生儿护士对父母痛苦的反思。
J Clin Nurs. 2015 Jul;24(13-14):1885-94. doi: 10.1111/jocn.12811. Epub 2015 May 4.
8
Pregnancy outcomes after assisted human reproduction.人类辅助生殖后的妊娠结局
J Obstet Gynaecol Can. 2014 Jan;36(1):64-83. doi: 10.1016/S1701-2163(15)30685-X.
9
Reproductive potential in the older woman.老年女性的生殖潜力。
Fertil Steril. 1986 Dec;46(6):989-1001. doi: 10.1016/s0015-0282(16)49869-9.
10
Assisted reproductive technology surveillance -- United States, 2010.辅助生殖技术监测--美国,2010 年。
MMWR Surveill Summ. 2013 Dec 6;62(9):1-24.

引用本文的文献

1
Future anxiety and the motives for postponing parenthood: generational time perspective and life satisfaction as mediators.未来焦虑与推迟生育的动机:代际时间视角和生活满意度作为中介因素
Front Psychol. 2025 Feb 12;15:1441927. doi: 10.3389/fpsyg.2024.1441927. eCollection 2024.
2
The Best Age for Pregnancy and Undue Pressures.怀孕的最佳年龄与不当压力
J Family Reprod Health. 2016 Sep;10(3):104-107.
3
Functional Human Oocytes Generated by Transfer of Polar Body Genomes.通过极体基因组转移产生的功能性人类卵母细胞。
Cell Stem Cell. 2017 Jan 5;20(1):112-119. doi: 10.1016/j.stem.2016.10.001. Epub 2016 Nov 10.
4
Mitochondrial replacement therapy in reproductive medicine.生殖医学中的线粒体替代疗法。
Trends Mol Med. 2015 Feb;21(2):68-76. doi: 10.1016/j.molmed.2014.12.001. Epub 2014 Dec 10.

本文引用的文献

1
Reproductive technologies and the risk of birth defects.生殖技术与出生缺陷的风险。
N Engl J Med. 2012 May 10;366(19):1803-13. doi: 10.1056/NEJMoa1008095. Epub 2012 May 5.
2
Similarly increased congenital anomaly rates after intrauterine insemination and IVF technologies: a retrospective cohort study.同样,宫腔内人工授精和体外受精技术后先天畸形发生率增加:一项回顾性队列研究。
Hum Reprod. 2012 Mar;27(3):902-9. doi: 10.1093/humrep/der443. Epub 2012 Jan 2.
3
Elective single embryo transfer and perinatal outcomes: a systematic review and meta-analysis.选择性单胚胎移植与围产结局:系统评价与荟萃分析。
Fertil Steril. 2012 Feb;97(2):324-31. doi: 10.1016/j.fertnstert.2011.11.033. Epub 2011 Dec 15.
4
Increased risk of brain injury in IVF babies.
Minerva Pediatr. 2011 Dec;63(6):445-8.
5
Changing families, changing workplaces.家庭在变,工作场所也在变。
Future Child. 2011 Fall;21(2):15-36. doi: 10.1353/foc.2011.0013.
6
Ovarian stimulation and low birth weight in newborns conceived through in vitro fertilization.体外受精受孕新生儿的卵巢刺激和低出生体重。
Obstet Gynecol. 2011 Oct;118(4):863-71. doi: 10.1097/AOG.0b013e31822be65f.
7
Advanced maternal age: delayed childbearing is rarely a conscious choice a qualitative study of women's views and experiences.高龄产妇:晚育很少是有意识的选择——一项关于女性观点和经验的定性研究。
Int J Nurs Stud. 2012 Jan;49(1):30-9. doi: 10.1016/j.ijnurstu.2011.07.013. Epub 2011 Aug 12.
8
Delayed childbearing: effects on fertility and the outcome of pregnancy.晚婚晚育:对生育能力和妊娠结局的影响。
Fetal Diagn Ther. 2011;29(4):263-73. doi: 10.1159/000323142. Epub 2011 Jan 12.
9
Reproductive 'choice' and egg freezing.生殖“选择”与卵子冷冻
Cancer Treat Res. 2010;156:223-35. doi: 10.1007/978-1-4419-6518-9_17.
10
Epigenetics, genomic imprinting and assisted reproductive technology.表观遗传学、基因组印迹和辅助生殖技术。
Ann Endocrinol (Paris). 2010 May;71(3):237-8. doi: 10.1016/j.ando.2010.02.004. Epub 2010 Apr 2.