Manley David W, Buzzetti Luca, MacKessack-Leitch Andrew, Walton John C
EaStCHEM School of Chemistry, University of St. Andrews, St. Andrews, Fife KY16 9ST, UK.
Molecules. 2014 Sep 24;19(9):15324-38. doi: 10.3390/molecules190915324.
A mild procedure for the reduction of electron-deficient alkenes and carbonyl compounds is described. UVA irradiations of substituted maleimides with dispersions of titania (Aeroxide P25) in methanol/acetonitrile (1:9) solvent under dry anoxic conditions led to hydrogenation and production of the corresponding succinimides. Aromatic and heteroaromatic aldehydes were reduced to primary alcohols in similar titania photocatalyzed reactions. A mechanism is proposed which involves two proton-coupled electron transfers to the substrates at the titania surface.
描述了一种用于还原缺电子烯烃和羰基化合物的温和方法。在干燥无氧条件下，用二氧化钛（气相二氧化钛P25）在甲醇/乙腈（1:9）溶剂中的分散体对取代马来酰亚胺进行紫外光照射，导致氢化并生成相应的琥珀酰亚胺。在类似的二氧化钛光催化反应中，芳香族和杂芳香族醛被还原为伯醇。提出了一种机制，该机制涉及在二氧化钛表面向底物进行两次质子耦合电子转移。
