Lefebvre D, Pirie R S, Handel I G, Tremaine W H, Hudson N P H
The Royal (Dick) School of Veterinary Studies and Roslin Institute, Easter Bush Veterinary Centre, University of Edinburgh, UK.
Department of Clinical Veterinary Science, University of Bristol, UK.
Equine Vet J. 2016 Mar;48(2):182-7. doi: 10.1111/evj.12355. Epub 2015 Jan 12.
There is a need for an improved understanding of equine post operative ileus (POI), in terms of both clinical definition and optimal management. Although the pharmacological strategies that are used to treat POI continue to evolve, little is known about the supplementary strategies used to prevent and manage this condition.
To report the current strategies used to diagnose, prevent and manage POI following emergency abdominal surgeries.
Cross-sectional survey.
An electronic survey invitation was sent by email to 306 European college diplomates (European Colleges of Equine Internal Medicine, ECEIM n = 120, and Veterinary Surgeons, ECVS n = 186).
The response rate was 33% (100 of 306). The median reported estimated incidence of POI was 10-20%. The presence of reflux on nasogastric intubation was the main criterion used to define POI. Lesions involving the small intestine were thought to be the leading risk factors for developing POI. Anti-inflammatory drugs, antimicrobial drugs and i.v. fluids were the primary preventative strategies when managing cases at high risk for POI. Flunixin meglumine and lidocaine were the drugs most commonly used to treat horses with POI. Supplementary preventative and treatment strategies for POI included control of endotoxaemia, fluid therapy, early ambulation and judicious timing of post operative feeding.
Appreciation of the potential risk factors associated with the development of POI appeared to have an impact on the choice of management strategies that are implemented. The majority of ECEIM and ECVS Diplomates in the survey used flunixin meglumine and lidocaine, often in combination, to treat horses with POI, which is likely to reflect the contributory role of inflammation in its pathophysiology. Various supplementary strategies were used to prevent and manage POI risk factors intraoperatively and post operatively.
在临床定义和最佳管理方面,需要进一步了解马的术后肠梗阻(POI)。尽管用于治疗POI的药物策略不断发展,但对于用于预防和管理这种情况的辅助策略知之甚少。
报告目前用于诊断、预防和管理紧急腹部手术后POI的策略。
横断面调查。
通过电子邮件向306名欧洲学院文凭持有者(欧洲马内科医师学院,ECEIM,n = 120;兽医外科医师,ECVS,n = 186)发送电子调查邀请。
回复率为33%(306人中100人)。报告的POI估计发病率中位数为10 - 20%。鼻胃插管时出现反流是定义POI的主要标准。涉及小肠的病变被认为是发生POI的主要危险因素。在管理POI高风险病例时,抗炎药、抗菌药和静脉输液是主要的预防策略。氟尼辛葡甲胺和利多卡因是最常用于治疗POI马匹的药物。POI的辅助预防和治疗策略包括控制内毒素血症、液体疗法、早期活动和术后喂养的合理时机。
认识到与POI发生相关的潜在危险因素似乎会影响所实施的管理策略的选择。调查中的大多数ECEIM和ECVS文凭持有者使用氟尼辛葡甲胺和利多卡因,通常联合使用,来治疗POI马匹,这可能反映了炎症在其病理生理学中的作用。术中及术后采用了各种辅助策略来预防和管理POI危险因素。