Al Zamel Ghada, Micheletti Robert G, Nasta Sunita D, Palakshappa Jessica, Stoopler Eric T
Former Resident, Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania.
Spec Care Dentist. 2015 May-Jun;35(3):143-7. doi: 10.1111/scd.12093. Epub 2014 Sep 26.
Paraneoplastic pemphigus (PNP) is a mucocutaneous disease that occurs in association with an underlying neoplasm. Oral mucosal lesions may be the only manifestation of this condition, or they may be observed in association with cutaneous lesions. The prognosis of PNP is generally poor, and the disease is often fatal. This article highlights an aggressive case of PNP that initially presented with oral mucosal lesions and emphasizes the importance of a multidisciplinary approach for evaluation and management of this condition.
副肿瘤性天疱疮（PNP）是一种与潜在肿瘤相关的皮肤黏膜疾病。口腔黏膜病变可能是这种疾病的唯一表现，也可能与皮肤病变同时出现。PNP的预后通常较差，该病往往是致命的。本文重点介绍了一例最初表现为口腔黏膜病变的侵袭性PNP病例，并强调了多学科方法在评估和管理这种疾病中的重要性。
