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根据肺功能对肺癌肺切除术进行风险评估:日本胸部外科学会指南委员会2014年系统评价的重新发表及建议

Risk assessment of lung resection for lung cancer according to pulmonary function: republication of systematic review and proposals by guideline committee of the Japanese association for chest surgery 2014.

作者信息

Sawabata Noriyoshi, Nagayasu Takashi, Kadota Yoshihisa, Goto Taichiro, Horio Hiroyoshi, Mori Takeshi, Yamashita Shinichi, Iwasaki Akinori

机构信息

Department of General Thoracic Surgery, Hoshigaoka Medical Center, Hirakata, Japan,

出版信息

Gen Thorac Cardiovasc Surg. 2015 Jan;63(1):14-21. doi: 10.1007/s11748-014-0475-x. Epub 2014 Sep 27.

Abstract

BACKGROUND

This manuscript provides preoperative physiologic assessments for patients considered for surgical resection of lung cancer.

METHODS

Medical studies of risk assessment of surgical resection for lung cancer according to pulmonary function were collected and a review article was written to present guidelines.

RESULTS

Preoperative physiologic assessment should begin with a cardiovascular evaluation, and spirometry to measure FEV 1 and the diffusing capacity of carbon monoxide (DLCo). Predicted postoperative (ppo) lung functions should also be calculated. If both %ppo-FEV 1 and %ppo-DLCo values are ≥ 60%, the patient is considered to be at low risk for anatomic lung resection. If either of those are <60% of the predicted value, an exercise test should be performed for screening. If performance on the exercise test is acceptable, the patient is regarded to be at low risk for anatomic resection. These findings can be summarized as an algorithm.

CONCLUSIONS

Careful preoperative physiologic assessment is useful for identifying patients at increased risk for standard lung cancer resection and enabling informed decisions by the patient about an appropriate therapeutic approach for their lung cancer.

摘要

背景

本手稿为考虑接受肺癌手术切除的患者提供术前生理评估。

方法

收集根据肺功能对肺癌手术切除风险评估的医学研究,并撰写一篇综述文章以呈现指南。

结果

术前生理评估应从心血管评估开始,并进行肺活量测定以测量第1秒用力呼气容积(FEV₁)和一氧化碳弥散量(DLCo)。还应计算预测术后(ppo)肺功能。如果ppo-FEV₁百分比和ppo-DLCo百分比均≥60%,则患者被认为进行肺解剖切除的风险较低。如果其中任何一项低于预测值的60%,则应进行运动试验以进行筛查。如果运动试验表现可接受,则患者被视为进行解剖切除的风险较低。这些发现可总结为一种算法。

结论

仔细的术前生理评估有助于识别标准肺癌切除风险增加的患者,并使患者能够就其肺癌的适当治疗方法做出明智的决定。

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