Moysich Axel, Happel Christoph M, Laser Kai T, Kececioglu Deniz, Haas Nikolaus A
Department of Congenital Heart Defects, Heart and Diabetes Centre North Rhine Westphalia, Ruhr University Bochum, Germany.
Catheter Cardiovasc Interv. 2015 Jun;85(7):1203-8. doi: 10.1002/ccd.25688. Epub 2015 Mar 24.
Interventional closure of patent ductus arteriosus (PDA) has become a common and safe procedure in most pediatric cath labs. Interventional treatment of PDAs still remains a challenge in those children with low body weight and a large PDA. The Nit-Occlud PDA-R® device was developed and especially designed for large PDAs. We report our most recent experience in children with a body weight lower than 10 kg.
The PDA-R® device was used in seven children (age 1-10, median 6 months) with a body weight from 4.1 to 9.7 kg (median 5.9 kg): ductal length was 12 mm (median), with a large ampulla (median 9 mm) which exceeded the diameter of the aorta (median 6 mm) and large diameter (median minimal diameter 4 mm). In six cases, the Nit-Occlud PDA-R was selected with an aortic disc of 12 mm and in one case an occluder with an aortic disc of 14 mm.
Occlusion of the PDA was documented by angiography and/or echocardiography in all cases. At a mean follow-up of 21.4 months, no flow obstruction to the left or right pulmonary artery or new onset coarctation of the aorta was noted.
The Nit-Occlud PDA-R® device is suitable in children with a body weight below 10 kg when a relative large PDA is present.
在大多数儿科心脏导管实验室中，动脉导管未闭（PDA）的介入封堵已成为一种常见且安全的手术。对于低体重且PDA较大的儿童，PDA的介入治疗仍然是一项挑战。Nit-Occlud PDA-R®装置被研发出来，专门用于治疗大型PDA。我们报告了我们在体重低于10kg儿童中的最新经验。
PDA-R®装置用于7名儿童（年龄1 - 10岁，中位数6个月），体重4.1至9.7kg（中位数5.9kg）：导管长度为12mm（中位数），壶腹较大（中位数9mm），超过主动脉直径（中位数6mm）且直径较大（中位数最小直径4mm）。6例选用主动脉盘直径为12mm的Nit-Occlud PDA-R，1例选用主动脉盘直径为14mm的封堵器。
所有病例经血管造影和/或超声心动图证实PDA封堵成功。平均随访21.4个月时，未发现左或右肺动脉血流受阻或新发主动脉缩窄。
当存在相对较大的PDA时，Nit-Occlud PDA-R®装置适用于体重低于10kg的儿童。
