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经导管闭合冠状动脉瘘伴 Nit-Occlud®未闭动脉导管线圈的中期随访。

Midterm follow up of transcatheter closure of coronary artery fistula with Nit-Occlud® patent ductus arteriosus coil.

机构信息

The Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

BMC Cardiovasc Disord. 2021 Apr 20;21(1):192. doi: 10.1186/s12872-021-01999-3.

Abstract

BACKGROUND

Coronary artery fistula (CAF) is a rare congenital anomaly with a challenging scenario in children. This study reports our experience in transcatheter closure of CAF with Nit-Occlude PDA coil and midterm clinical and imaging follow-up.

METHODS

Twelve children with congenital CAF between 2009 and 2019, mean age 2.05 ± 2.05 years (4 days to 7.2 years), mean weight 8.8 ± 4.83 (2.8-17 kg), who underwent transcatheter closure with PFM coil at the Namazi hospital, Shiraz, Iran, were reported. Echocardiography and electrocardiogram were done before and after the procedure (early, 3, and 6 months after), and Multi-slice computerized tomography or conventional coronary angiography was performed at least one year after closure.

RESULTS

In a median follow-up of 5.5 years (range 13 months to 8 years), retrogradely closed fistula had no residual, and the fistula tract was wholly occluded, but in most anterogradely closed fistula, had a small residual, which made the fistula tract open and need additional coil closure.

CONCLUSIONS

Transcatheter closure of CAF with PFM coil is feasible and effective with low mortality and morbidity, although antegrade closure with this device may be accompanied by residual shunt and need for multiple coil insertion.

摘要

背景

冠状动脉瘘(CAF)是一种罕见的先天性异常,在儿童中具有挑战性。本研究报告了我们使用 Nit-Occlude PDA 线圈经导管封堵 CAF 的经验,并进行了中期临床和影像学随访。

方法

2009 年至 2019 年间,我们在伊朗设拉子的 Namazi 医院对 12 例先天性 CAF 患儿(平均年龄 2.05±2.05 岁,范围为 4 天至 7.2 岁;平均体重 8.8±4.83kg,范围为 2.8-17kg)进行了经导管封堵术,使用的器械为 PFM 线圈。在术前、术后即刻(术后 3 个月和 6 个月)以及至少 1 年(术后 1 年)进行了超声心动图和心电图检查,还进行了多层计算机断层扫描或常规冠状动脉造影检查。

结果

中位随访时间为 5.5 年(范围为 13 个月至 8 年),发现逆行性关闭的瘘管无残余,瘘管通道完全闭塞,但大多数顺行性关闭的瘘管存在小残余,导致瘘管通道开放,需要额外的线圈闭合。

结论

使用 PFM 线圈经导管封堵 CAF 是可行且有效的,具有较低的死亡率和发病率,但使用这种器械进行顺行封堵可能会伴有残余分流,需要多次插入线圈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de61/8056487/ee2c7c32813c/12872_2021_1999_Fig1_HTML.jpg

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