Chung Jae Ho, Moon Kitae, Kim Do Hyung, Min Joo-Won, Kim Tae Ho, Hwang Hee-Jin
Department of Internal Medicine, International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Republic of Korea.
The Korean Society for Preventive Medicine, Seoul, Republic of Korea.
J Psychosom Res. 2014 Dec;77(6):457-61. doi: 10.1016/j.jpsychores.2014.08.008. Epub 2014 Aug 29.
The present study evaluated the mental health of patients with diabetes mellitus (DM) in Korea and compared it with mental health in the general Korean population.
All data included in the final analyses were collected from 34,065 subjects (20years of age or older) who participated in the 2007-2012 Korea National Health and Nutrition Examination Survey (KNHANES). The mental health of 3846 DM patients were compared with that of 30,219 controls.
A depressed mood for 2 or more continuous weeks was reported by 13.6% of subjects with normal glucose tolerance (NGT), 14.3% of those with impaired glucose intolerance (IFG), and 17.6% of DM patients. Suicidal thoughts were reported by 15.3% of individuals with NGT, 15.6% of participants with IFG, and 17.6% of DM patients. Suicidal attempts were reported by 0.8% of people with NGT, 1.0% of those with IFG, and 1.3% of DM patients. In DM patients, the crude odds ratio (OR) for depressive mood was 1.376 (95% confidence interval [CI]: 1.258-1.504), the OR for suicidal ideation was 1.481 (95% CI: 1.361-1.611) and the OR for suicidal attempts was 1.413 (95% CI: 1.021-1.956). A multivariate analysis revealed that the ORs for depression, suicidal ideation, and suicidal attempts in DM patients were 1.178 (95% CI: 1.070-1.297), 1.152 (95% CI: 1.050-1.263), and 1.413 (95% CI: 1.021-1.956), respectively.
The present study found that DM was associated with a marked increase in suicidal behaviors.
本研究评估了韩国糖尿病患者的心理健康状况,并将其与韩国普通人群的心理健康状况进行比较。
最终分析中纳入的所有数据均来自于参与2007 - 2012年韩国国家健康与营养检查调查(KNHANES)的34,065名受试者(年龄在20岁及以上)。将3846名糖尿病患者的心理健康状况与30,219名对照者进行比较。
血糖耐量正常(NGT)的受试者中有13.6%报告持续两周或更长时间情绪低落,糖耐量受损(IFG)者中有14.3%,糖尿病患者中有17.6%。NGT个体中有15.3%报告有自杀念头,IFG参与者中有15.6%,糖尿病患者中有17.6%。NGT人群中有0.8%报告有自杀未遂行为,IFG者中有1.0%,糖尿病患者中有1.3%。在糖尿病患者中,抑郁情绪的粗比值比(OR)为1.376(95%置信区间[CI]:1.258 - 1.504),自杀意念的OR为1.481(95%CI:1.361 - 1.611),自杀未遂的OR为1.413(95%CI:1.021 - 1.956)。多因素分析显示,糖尿病患者抑郁、自杀意念和自杀未遂的OR分别为1.178(95%CI:1.070 - 1.297)、1.152(95%CI:1.050 - 1.263)和1.413(95%CI:1.021 - 1.956)。
本研究发现糖尿病与自杀行为显著增加有关。