慢性阻塞性肺疾病患者的自杀意念和自杀企图：来自 2007-2012 年韩国国家健康和营养调查（KNHANES IV、V）的研究。
Suicidal ideation and suicide attempts in chronic obstructive pulmonary disease: the Korea National Health and Nutrition Examination Survey (KNHANES IV, V) from 2007-2012.
机构信息
Division of Pulmonology, Department of Internal Medicine, International St. Mary`s Hospital, Catholic Kwandong University College of Medicine, Incheon, Republic of Korea.
Division of Pulmonology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Koyang, Republic of Korea.
出版信息
NPJ Prim Care Respir Med. 2014 Oct 30;24:14094. doi: 10.1038/npjpcrm.2014.94.
BACKGROUND
There is good evidence for an association between chronic obstructive pulmonary disease (COPD) and depression, but there are few studies on the relationship between COPD and suicidal ideation/suicidal attempts.
AIMS
To evaluate the mental health of patients with COPD in Korea and to compare it with that of the general population.
METHODS
We analysed data of 15,718 subjects (age ⩾40 years) who participated in the 2007-2012 Korea National Health and Nutrition Examination Survey. COPD was defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria for people aged ⩾40 years. We compared the mental health outcomes of 2,506 patients with COPD (2,355 GOLD stages I and II; 151 GOLD stages III and IV) with those of 13,212 controls.
RESULTS
Suicidal thoughts were reported by 16.0% of patients in stages I and II, by 23.8% of those in stages III and IV and by 15.7% of controls (P=0.023). Suicidal attempts were reported by 0.6% of patients in stages I and II, by 2.6% of those in stages III and IV and by 1.0% of controls (P=0.019). The crude odds ratio (OR) for suicidal ideation in those in stages III and IV was 1.68 (95% confidence interval (CI), 1.16-2.46), and the OR for suicidal attempts in stages III and IV was 2.83 (95% CI, 1.03-7.75). In multivariate analysis, the OR for suicidal ideation in stages III and IV was 1.67 (95% CI, 1.12-2.49) and that for suicidal attempts was 2.94 (95% CI, 1.03-8.31).
CONCLUSIONS
GOLD stages III and IV COPD were associated with a marked increase in suicidal behaviour.
背景
有充分的证据表明慢性阻塞性肺疾病（COPD）与抑郁之间存在关联，但关于 COPD 与自杀意念/自杀企图之间的关系的研究较少。
目的
评估韩国 COPD 患者的心理健康状况，并将其与普通人群进行比较。
方法
我们分析了 2007-2012 年韩国国家健康和营养检查调查中 15718 名（年龄≥40 岁）受试者的数据。COPD 根据全球倡议慢性阻塞性肺疾病（GOLD）标准定义为年龄≥40 岁的人群。我们比较了 2506 例 COPD 患者（GOLD 分期 I 和 II 为 2355 例；GOLD 分期 III 和 IV 为 151 例）与 13212 名对照者的心理健康结局。
结果
I 期和 II 期患者报告有自杀念头的比例为 16.0%，III 期和 IV 期患者为 23.8%，对照组为 15.7%（P=0.023）。I 期和 II 期患者报告有自杀企图的比例为 0.6%，III 期和 IV 期患者为 2.6%，对照组为 1.0%（P=0.019）。III 期和 IV 期患者自杀意念的粗比值比（OR）为 1.68（95%置信区间（CI），1.16-2.46），III 期和 IV 期患者自杀企图的 OR 为 2.83（95%CI，1.03-7.75）。多变量分析显示，III 期和 IV 期患者自杀意念的 OR 为 1.67（95%CI，1.12-2.49），自杀企图的 OR 为 2.94（95%CI，1.03-8.31）。
结论
GOLD 分期 III 期和 IV 期 COPD 与自杀行为明显增加有关。
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