Nemoto Yuji, Arita Reiko, Mizota Atsushi, Sasajima Yuko
Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan.
Itoh Clinic, Saitama, The University of Tokyo, Tokyo, Japan ; Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Clin Ophthalmol. 2014 Sep 18;8:1869-75. doi: 10.2147/OPTH.S69804. eCollection 2014.
Sebaceous carcinoma is notorious for masquerading clinically as other benign lesions such as chalazion. A tool to better differentiate between these two conditions would thus be desirable.
To examine the potential application of noninvasive meibography in the differential diagnosis of chalazion and sebaceous carcinoma of the eyelid as a retrospective cross-sectional study.
Five individuals with chalazion and three patients with sebaceous carcinoma were observed. Noninvasive meibography was performed to visualize the reflectivity and shape of the lesion in each subject.
Noninvasive meibographic imaging revealed chalazion as a lesion of overall low reflectivity with small regions of higher reflectivity corresponding to lipid granules. On the other hand, the noninvasive meibography revealed sebaceous carcinoma as a poorly marginated lesion of high reflectivity in the eyelid.
Noninvasive meibographic imaging may prove useful for the differential diagnosis of chalazion and sebaceous carcinoma. It may also be informative in definition of the resection area in carcinoma patients.
皮脂腺癌在临床上常伪装成睑板腺囊肿等其他良性病变，因而臭名昭著。因此，需要一种能更好地区分这两种情况的工具。
作为一项回顾性横断面研究，探讨无创睑板腺造影在睑板腺囊肿和眼睑皮脂腺癌鉴别诊断中的潜在应用。
观察5例睑板腺囊肿患者和3例皮脂腺癌患者。对每位受试者进行无创睑板腺造影，以观察病变的反射率和形态。
无创睑板腺造影成像显示，睑板腺囊肿为整体低反射率病变，有对应于脂质颗粒的小区域高反射率。另一方面，无创睑板腺造影显示皮脂腺癌为眼睑中边界不清的高反射率病变。
无创睑板腺造影成像可能对睑板腺囊肿和皮脂腺癌的鉴别诊断有用。它在确定癌症患者的切除范围方面也可能提供信息。
