Kovach R, Goldberg S
Department of Medicine, Thomas Jefferson University, Philadelphia, Pa 19107.
Cardiology. 1989;76(2):158-66. doi: 10.1159/000174486.
Residual myocardial function has been shown by many investigators to be a key factor in determining survival following acute myocardial infarction. In light of this, much effort has been undertaken to develop means of preserving myocardium in the setting of acute myocardial infarction. Acute revascularization has been approached as a logical method to reach this end. The development of more effective thrombolytic agents, better catheter dilatation systems, and improved surgical techniques have now made acute intervention possible, safe, and practical. Because of the marked clinical variability of patient presentation, as well as variability of available medical and surgical resources, a rational and logical system of approach must be developed, such that patients presenting with acute myocardial infarction can receive the most appropriate interventional therapy in any given setting.
许多研究人员已表明,残余心肌功能是决定急性心肌梗死后生存率的关键因素。鉴于此,人们已付出诸多努力来研发在急性心肌梗死情况下保护心肌的方法。急性血运重建已被视为实现这一目标的合理方法。更有效的溶栓剂、更好的导管扩张系统以及改进的手术技术的发展,现已使急性干预成为可能、安全且切实可行。由于患者临床表现存在显著的临床变异性,以及可用医疗和手术资源的变异性,必须制定一个合理且合乎逻辑的治疗体系,以便使急性心肌梗死患者在任何特定情况下都能接受最合适的介入治疗。