Cohn L H
Harvard Medical School, Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, Mass 02115.
Cardiology. 1989;76(2):167-72. doi: 10.1159/000174487.
In 1989 the following indications for surgical treatment of acute myocardial infarction are: (1) acute evolving myocardial infarction less than 6 h from onset, in patients in whom percutaneous transluminal coronary angioplasty (PTCA) or streptokinase (SK), depending on the coronary anatomy, has been unsuccessful; if single vessel disease, coronary artery bypass grafting (CABG) is unlikely; if multiple vessel disease, CABG is preferable to SK/PTCA unless a very major 'culprit' lesion can be identified with certainty; (2) postinfarction angina hours to days after a transmural myocardial infarction unyielding to maximal medical therapy and in patients with a coronary artery obstruction not amenable to PTCA; (3) occlusion of a coronary artery during cardiac catheterization that cannot be fixed by PTCA and/or SK; (4) occlusion of a coronary artery during PTCA causing hemodynamic obstruction and a threatened myocardium subtended by the obstructed coronary artery; (5) balloon-dependent patients in cardiogenic shock without mechanical defects who have adequate residual left ventricular function as determined by regional wall motion studies; (6) ventricular septal defect secondary to myocardial infarction unless there is terminal organ damage; (7) mitral valve replacement with coronary bypass for acute papillary muscle rupture; (8) semi-emergency cardiac transplantation, either with or without a mechanical bridge to transplant in young individuals (less than 50 years) who have suffered massive destruction of left ventricular myocardium by an acute coronary occlusion with or without recurring ventricular tachyarrhythmias. Ejection fraction in this clinical category is always under 0.20 and usually under 0.15.
1989年,急性心肌梗死外科治疗的指征如下:(1)起病后6小时内急性进展性心肌梗死,根据冠状动脉解剖情况,经皮腔内冠状动脉成形术(PTCA)或链激酶(SK)治疗失败的患者;若为单支血管病变,冠状动脉旁路移植术(CABG)不太可能实施;若为多支血管病变,除非能明确确定一个非常主要的“罪犯”病变,否则CABG比SK/PTCA更可取;(2)透壁性心肌梗死后数小时至数天发生的梗死后心绞痛,经最大程度药物治疗无效,且冠状动脉阻塞无法进行PTCA治疗的患者;(3)心导管检查期间冠状动脉闭塞,无法通过PTCA和/或SK修复;(4)PTCA期间冠状动脉闭塞,导致血流动力学障碍,且阻塞冠状动脉所供血的心肌受到威胁;(5)因心源性休克依赖球囊辅助的患者,无机械性缺陷,经局部室壁运动研究确定左心室功能有足够的残余功能;(6)心肌梗死继发室间隔缺损,除非存在终末器官损害;(7)急性乳头肌破裂行二尖瓣置换并冠状动脉搭桥;(8)半急诊心脏移植,适用于因急性冠状动脉闭塞导致左心室心肌大量破坏且伴有或不伴有复发性室性心律失常的年轻患者(小于50岁),无论有无机械性桥接至移植。这一临床类别的射血分数始终低于0.20,通常低于0.15。