单脐动脉妊娠中的脐动脉血流：一项前瞻性病例对照研究。
Umbilical artery blood flows among pregnancies with single umbilical artery: a prospective case-control study.
作者信息
Baron Joel, Weintraub Adi Y, Sciaky Yael, Mastrolia Salvatore A, Speigel Efrat, Hershkovitz Reli
机构信息
a Department of Obstetrics and Gynecology , Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev , Israel and.
出版信息
J Matern Fetal Neonatal Med. 2015;28(15):1803-5. doi: 10.3109/14767058.2014.968845. Epub 2014 Oct 13.
OBJECTIVES
To evaluate peak systolic velocity (PSV) in the umbilical artery (UA) among patients with single umbilical artery (SUA) as compared with patients with three vessel cords.
METHODS
A prospective case-control study was performed. UA blood flow velocimetry was obtained from fetuses with SUA and from a control group with three vessel cord. PSV and pulsatility index (PI) were measured. Patients' characteristics were compared for statistical differences and a linear regression model was constructed for the different groups.
RESULTS
UA Doppler velocimetry measurements were obtained from 29 patients with SUA and from 29 controls matched for gestational age. The differences between UA PI with and without SUA were significant (F = 3.471; p = 0.0379) showing a lower PI in the SUA group. However, no significant statistical difference was found in PSV between these two groups (F = 0.149; p = 0.86).
CONCLUSIONS
While the impedance in the UA of patients with a SUA was lower compared with patients with a normal umbilical cord, the PSV did not differ.
目的
评估单脐动脉（SUA）患者与三血管脐带患者相比，脐动脉（UA）的收缩期峰值流速（PSV）。
方法
进行一项前瞻性病例对照研究。从患有SUA的胎儿和三血管脐带的对照组中获取UA血流速度测量值。测量PSV和搏动指数（PI）。比较患者特征的统计学差异，并为不同组构建线性回归模型。
结果
从29例患有SUA的患者和29例孕周匹配的对照组中获得了UA多普勒血流速度测量值。有和没有SUA的UA PI之间的差异具有统计学意义（F = 3.471；p = 0.0379），显示SUA组的PI较低。然而，这两组之间的PSV没有发现显著的统计学差异（F = 0.149；p = 0.86）。
结论
虽然与正常脐带患者相比，SUA患者的UA阻抗较低，但PSV没有差异。
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