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双脐动脉至单脐动脉伴低搏动指数导致胎儿死亡:一例报告及文献复习

Double-to-Single Umbilical Artery With a Low Pulsatility Index Leading to Fetal Death: A Case Report and Review of Literature.

作者信息

Lin Yanting, Yan Ruiling, He Andong, Chen Jie, Li Ruiman

机构信息

Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, CHN.

Obstetrics and Gynecology, The Affiliated Shunde Hospital of Jinan University, Guangzhou, CHN.

出版信息

Cureus. 2023 Dec 29;15(12):e51273. doi: 10.7759/cureus.51273. eCollection 2023 Dec.

DOI:10.7759/cureus.51273
PMID:38283532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10822057/
Abstract

Single umbilical artery (SUA) may be associated with adverse pregnancy outcomes, such as fetal death, emergency cesarean section, premature delivery, small-for-gestational-age infants, and admission to neonatal intensive care unit, and some SUAs are transformed from originally double umbilical arteries (UA). The pulsatility index (PI) can reflect the resistance of UA, and clinicians attach importance to high PI but easily overlook low levels of it. We reported one case of a pregnant woman who underwent double to single UA accompanied by low UA-PI and finally had intrauterine fetal death. Additionally, the literature regarding SUA and UA-PI is reviewed. This study aims to alert clinicians to the risk of double-to-single UA with low UA-PI and strengthen fetal monitoring and timely intervention. We look forward to more clinical evidence to investigate it.

摘要

单脐动脉(SUA)可能与不良妊娠结局相关,如胎儿死亡、急诊剖宫产、早产、小于胎龄儿以及入住新生儿重症监护病房,并且一些SUA是由原本的双脐动脉(UA)转变而来。搏动指数(PI)可反映UA的阻力,临床医生重视高PI但容易忽视低PI情况。我们报告了1例孕妇,其UA从双变单并伴有低UA-PI,最终发生宫内胎儿死亡。此外,对关于SUA和UA-PI的文献进行了综述。本研究旨在提醒临床医生注意UA从双变单且伴有低UA-PI的风险,加强胎儿监测并及时干预。我们期待有更多临床证据对此进行研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed74/10822057/e9dccf7b5976/cureus-0015-00000051273-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed74/10822057/96acf88e6ecc/cureus-0015-00000051273-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed74/10822057/fbaa3a4f783e/cureus-0015-00000051273-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed74/10822057/e9dccf7b5976/cureus-0015-00000051273-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed74/10822057/96acf88e6ecc/cureus-0015-00000051273-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed74/10822057/fbaa3a4f783e/cureus-0015-00000051273-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed74/10822057/e9dccf7b5976/cureus-0015-00000051273-i03.jpg

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本文引用的文献

1
Prenatal diagnosis of single umbilical artery and postpartum outcome.单脐动脉的产前诊断及产后结局
Eur J Obstet Gynecol Reprod Biol. 2020 Nov;254:6-10. doi: 10.1016/j.ejogrb.2020.08.047. Epub 2020 Sep 2.
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Umbilical artery thrombosis: Two case reports.脐动脉血栓形成:两例病例报告。
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Umbilical Artery Thrombosis with Associated Acute and Severe Fetal Growth Restriction and Transient Severe Protein S Deficiency: Report of a Case with Prenatal Ultrasound Diagnosis Allowing for Timely Intervention and Good Outcome.
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Thrombosis of the umbilical vessels revisited. An observational study of 317 consecutive autopsies at a single institution.重新探讨脐带血栓。单中心连续 317 例尸检的观察性研究。
Hum Pathol. 2010 Jul;41(7):971-9. doi: 10.1016/j.humpath.2009.07.026. Epub 2010 Mar 17.