Mat Baki M, Wood G, Alston M, Ratcliffe P, Sandhu G, Rubin J S, Birchall M A
Ear Institute, University College London, London, UK; Royal National Throat Nose Ear Hospital, University College London Hospital NHS Trust, London, UK; Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Clin Otolaryngol. 2015 Feb;40(1):22-8. doi: 10.1111/coa.12313.
To evaluate the agreement between OperaVOX and MDVP.
Cross sectional reliability study.
University teaching hospital.
Fifty healthy volunteers and 50 voice disorder patients had supervised recordings in a quiet room using OperaVOX by the iPod's internal microphone with sampling rate of 45 kHz. A five-seconds recording of vowel/a/was used to measure fundamental frequency (F0), jitter, shimmer and noise-to-harmonic ratio (NHR). All healthy volunteers and 21 patients had a second recording. The recorded voices were also analysed using the MDVP. The inter- and intrasoftware reliability was analysed using intraclass correlation (ICC) test and Bland-Altman (BA) method. Mann-Whitney test was used to compare the acoustic parameters between healthy volunteers and patients.
Nine of 50 patients had severe aperiodic voice. The ICC was high with a confidence interval of >0.75 for the inter- and intrasoftware reliability except for the NHR. For the intersoftware BA analysis, excluding the severe aperiodic voice data sets, the bias (95% LOA) of F0, jitter, shimmer and NHR was 0.81 (11.32, -9.71); -0.13 (1.26, -1.52); -0.52 (1.68, -2.72); and 0.08 (0.27, -0.10). For the intrasoftware reliability, it was -1.48 (18.43, -21.39); 0.05 (1.31, -1.21); -0.01 (2.87, -2.89); and 0.005 (0.20, -0.18), respectively. Normative data from the healthy volunteers were obtained. There was a significant difference in all acoustic parameters between volunteers and patients measured by the Opera-VOX (P < 0.001) except for F0 in females (P = 0.87).
OperaVOX is comparable to MDVP and has high internal consistency for measuring the F0, jitter and shimmer of voice except for the NHR.
评估OperaVOX与MDVP之间的一致性。
横断面可靠性研究。
大学教学医院。
50名健康志愿者和50名嗓音障碍患者在安静房间内使用OperaVOX通过iPod内置麦克风进行监督录音，采样率为45kHz。使用元音/a/的5秒录音来测量基频（F0）、抖动、闪烁和噪声谐波比（NHR）。所有健康志愿者和21名患者进行了第二次录音。录制的声音也使用MDVP进行分析。使用组内相关系数（ICC）检验和布兰德-奥特曼（BA）方法分析软件间和软件内的可靠性。使用曼-惠特尼检验比较健康志愿者和患者之间的声学参数。
50名患者中有9名存在严重的非周期性嗓音。除NHR外，软件间和软件内可靠性的ICC较高，置信区间>0.75。对于软件间BA分析，排除严重非周期性嗓音数据集后，F0、抖动、闪烁和NHR的偏差（95%一致性界限）分别为0.81（11.32，-9.71）；-0.13（1.26，-1.52）；-0.52（1.68，-2.72）；以及0.08（0.27，-0.10）。对于软件内可靠性，分别为-1.48（18.43，-21.39）；0.05（1.31，-1.21）；-0.01（2.87，-2.89）；以及0.005（0.20，-0.18）。获得了健康志愿者的标准数据。通过Opera-VOX测量，志愿者和患者之间所有声学参数均存在显著差异（P<0.001），女性的F0除外（P=0.87）。
OperaVOX与MDVP相当，在测量嗓音的F0、抖动和闪烁方面具有较高的内部一致性，但NHR除外。
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