Addetia Karima, Patel Amit R
Department of Medicine, Section of Cardiology, University of Chicago Medical Center, 5841 South Maryland Avenue, MC5084, Chicago, Illinois 60637, USA.
Expert Rev Cardiovasc Ther. 2014 Nov;12(11):1269-73. doi: 10.1586/14779072.2014.965147. Epub 2014 Sep 29.
Historically, the right ventricle (RV) has received less attention than the left probably because morbidity and mortality associated with left ventricular disease is clinically more apparent. Right heart disease, in contrast, tends to have a more prolonged and, in the early stages, often subclinical course. Furthermore, the left ventricle is easier to image, model and quantify, so that research has been successful at amassing a great deal of clinically useful information about the left heart while the right heart still remains, in many ways, a mystery. In this perspective, the authors sought to explore the topic of RV recovery potential that has important clinical implications in the evaluation and treatment of advanced right-sided valvular heart disease, congenital heart disease, pulmonary arterial disease and even lung disease which impacts the RV. We see a clear need for a better understanding of RV viability given our increasing appreciation that RV failure is a significant contributor to morbidity and mortality in many disease states and the fact that newer imaging modalities and innovative changes to older modalities make more comprehensive evaluation of the RV feasible.
从历史上看，右心室（RV）受到的关注比左心室少，这可能是因为与左心室疾病相关的发病率和死亡率在临床上更为明显。相比之下，右心疾病往往病程更长，且在早期通常处于亚临床阶段。此外，左心室更容易成像、建模和量化，因此研究成功积累了大量关于左心的临床有用信息，而右心在很多方面仍是一个谜。从这个角度来看，作者试图探讨右心室恢复潜力这一主题，它在晚期右侧瓣膜性心脏病、先天性心脏病、肺动脉疾病甚至影响右心室的肺部疾病的评估和治疗中具有重要的临床意义。鉴于我们越来越认识到右心室衰竭是许多疾病状态下发病率和死亡率的重要因素，以及新的成像方式和对旧方式的创新变革使对右心室进行更全面的评估成为可能，我们清楚地认识到有必要更好地了解右心室的生存能力。
