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颈椎浸润性肌内黏液瘤:一例报告

Infiltrative intramuscular myxoma of the cervical spine: a case report.

作者信息

Manoharan Sakthivel Rajan Rajaram, Shaw Andrew B, Arnold Christina A, Farhadi H Francis

机构信息

Department of Neurological Surgery, Ohio State University Wexner Medical Center, 410 W. 10th Ave., Columbus, Ohio 43210, USA.

Department of Pathology, Ohio State University Wexner Medical Center, 410 W. 10th Ave., Columbus, Ohio 43210, USA.

出版信息

Spine J. 2015 Jan 1;15(1):e1-4. doi: 10.1016/j.spinee.2014.09.008. Epub 2014 Sep 28.

Abstract

BACKGROUND CONTEXT

Myxomas are benign tumors of mesenchymal cell origin that usually present as solitary lesions. They are infrequently associated with fibrous dysplasia, as in McCune-Albright or Mazabraud syndrome. Myxomas can develop in a variety of locations, although the most frequent sites are the thigh, buttocks, shoulder, and upper arm. Intramuscular myxomas (IMs) refer to lesions that occur within muscle compartments. They have been infrequently reported in the neck musculature.

PURPOSE

To date, only five cases have been reported within the posterior neck muscles without associated intraspinal extension. To our knowledge, this is the first case of an IM presenting with extension into the spinal canal.

STUDY DESIGN

We report a case of posterior cervical IM with intraspinal extension presenting in a 63-year-old woman as a palpable mass.

METHODS

Complete intralesional resection of the tumor was achieved by standard midline posterior approach. Meticulous resection of the entire capsule was achieved and all margins were confirmed to be free of neoplasm.

RESULTS

A diagnosis of myxoma was provided on pathologic evaluation. Follow-up at 1.5 years confirmed maintained complete resolution of the preoperative symptoms, with no evidence of local recurrence on imaging.

CONCLUSIONS

Intramuscular myxomas should be included in the differential diagnosis of cervical paraspinal tumors. Furthermore, we suggest that masses involving the axial muscles should be closely monitored and the patient counseled regarding potential neurologic sequelae.

摘要

背景

黏液瘤是间充质细胞起源的良性肿瘤,通常表现为孤立性病变。它们很少与纤维发育不良相关,如McCune - Albright综合征或Mazabraud综合征。黏液瘤可发生于多种部位,尽管最常见的部位是大腿、臀部、肩部和上臂。肌内黏液瘤(IMs)是指发生在肌肉间隙内的病变。它们在颈部肌肉组织中很少见。

目的

迄今为止,仅报道了5例后颈部肌肉内的病例,且无椎管内延伸。据我们所知,这是首例肌内黏液瘤延伸至椎管内的病例。

研究设计

我们报告了1例63岁女性患者,其表现为可触及肿块的颈椎后肌内黏液瘤并伴有椎管内延伸。

方法

通过标准的后正中入路实现肿瘤的完整瘤内切除。实现了对整个包膜的细致切除,所有切缘均证实无肿瘤。

结果

病理评估确诊为黏液瘤。1.5年的随访证实术前症状完全缓解,影像学检查无局部复发迹象。

结论

肌内黏液瘤应纳入颈椎旁肿瘤的鉴别诊断。此外,我们建议对累及轴性肌肉的肿块进行密切监测,并告知患者潜在的神经后遗症。

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