Heymans O, Gebhart M, Alexiou J, de Saint Aubain N, Larsimont D
Department of Orthopaedic Surgery, Bordet Institute, Brussels, Belgium.
Acta Chir Belg. 1998 Jun;98(3):120-2.
Intramuscular myxoma is a rare, benign, mesenchymal tumour. It contains fibroblast-like, histiocyt-like and myofibroblast-like cells in a myxoid material. These tumours occur in adults between 40 and 60 years with a predilection for women (70%). The incidence varies between 0.10 and 0.13/100.000. They may occur as an independent lesion or in conjunction with fibrous dysplasia or Albright syndrome. Although only circumstantial features have linked fibrous dysplasia and myxoma, the concept of a basic metabolic error of both tissues during initial growth period has been proposed. There are no specific clinical manifestations of this tumour. Although MRI offers the best imaging approach in terms of determination of the local extension of the tumour and its fatty texture, the differential diagnosis between intramuscular myxoma and myxoid degenerescence of a liposarcoma must be considered. The diagnosis is always made after microscopic examination. Local excision with histological margins free of tumour provides excellent local control without recurrence. The case of a patient presenting this rare tumour is presented. A thorough survey of the literature was done.
肌内黏液瘤是一种罕见的良性间叶组织肿瘤。它在黏液样物质中含有成纤维细胞样、组织细胞样和肌成纤维细胞样细胞。这些肿瘤发生于40至60岁的成年人，女性更为多见（70%）。发病率在0.10至0.13/10万之间。它们可作为独立病变出现，或与纤维发育不良或奥尔布赖特综合征同时发生。尽管仅有间接证据将纤维发育不良和黏液瘤联系起来，但有人提出了两种组织在初始生长阶段存在基本代谢错误的概念。这种肿瘤没有特异性临床表现。尽管就确定肿瘤的局部范围及其脂肪质地而言，MRI提供了最佳的成像方法，但必须考虑肌内黏液瘤与脂肪肉瘤黏液样变性之间的鉴别诊断。诊断总是在显微镜检查后做出。进行局部切除并确保组织学切缘无肿瘤，可实现良好的局部控制且不复发。本文介绍了一名患有这种罕见肿瘤的患者的病例。并对文献进行了全面综述。
