Atluri Pavan, Goldstone Andrew B, Fox Jeanne, Szeto Wilson Y, Hargrove W Clark
Division of Cardiovascular Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Division of Cardiovascular Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Ann Thorac Surg. 2014 Nov;98(5):1579-83; discussion 1583-4. doi: 10.1016/j.athoracsur.2014.06.051. Epub 2014 Sep 27.
Minimally invasive, right thoracotomy (port access) approaches to intracardiac operations (mitral valve, tricuspid valve, atrial septal defect, intracardiac tumors) are becoming increasingly accepted by surgeons, cardiologists, and patients alike. Standard techniques for cardioplegic arrest of the heart have included endoaortic balloons and Chitwood clamps. Concerns have been raised regarding the potential increased risk of vascular adverse events (embolization, dissection, stroke, lower extremity ischemia) associated with endoaortic balloon occlusion. We undertook this study to evaluate the vascular risk associated with endoaortic balloon use.
All patients undergoing minimally invasive, port access, right thoracotomy operations from 1998 to 2012 at our institution were retrospectively analyzed. Patients undergoing aortic occlusion with the Chitwood clamp (n=189) were compared with patients undergoing occlusion with the endoaortic balloon (n=875).
There was no statistical difference in the rate of dissection between patients undergoing aortic occlusion with an endoaortic balloon (1.03%) and those receiving a Chitwood clamp (1.06%). Similarly, there was no difference in the rate of type A dissection between aortic occlusion strategies (endoaortic balloon=0.57%, n=5, vs Chitwood clamp=1.06%, n=2, p=0.28). No difference in the incidence of stroke was identified between the endoaortic balloon and the Chitwood clamp (2.2% vs 2.1%, p=1.0).
Minimally invasive cardiac operations using a peripheral cannulation strategy can be safely performed with minimal vascular adverse events incorporating either endoaortic balloon or Chitwood clamp aortic occlusion. As experience with the endoaortic balloon is gained, the incidence of vascular adverse events can be reduced to nearly negligible rates.
心脏内手术(二尖瓣、三尖瓣、房间隔缺损、心脏肿瘤)的微创右胸切口(端口入路)方法越来越受到外科医生、心脏病专家和患者的认可。心脏停搏的标准技术包括主动脉内球囊和奇伍德夹。人们对与主动脉内球囊阻断相关的血管不良事件(栓塞、夹层、中风、下肢缺血)的潜在风险增加表示担忧。我们进行这项研究以评估使用主动脉内球囊的血管风险。
回顾性分析1998年至2012年在我们机构接受微创端口入路右胸切口手术的所有患者。将使用奇伍德夹进行主动脉阻断的患者(n = 189)与使用主动脉内球囊进行阻断的患者(n = 875)进行比较。
使用主动脉内球囊进行主动脉阻断的患者(1.03%)与接受奇伍德夹的患者(1.06%)之间的夹层发生率无统计学差异。同样,主动脉阻断策略之间的A型夹层发生率也无差异(主动脉内球囊 = 0.57%,n = 5,vs奇伍德夹 = 1.06%,n = 2,p = 0.28)。主动脉内球囊和奇伍德夹之间未发现中风发生率的差异(2.2%对2.1%,p = 1.0)。
采用外周插管策略的微创心脏手术可以安全地进行,使用主动脉内球囊或奇伍德夹进行主动脉阻断时,血管不良事件最少。随着对主动脉内球囊经验的积累,血管不良事件的发生率可降低到几乎可以忽略不计的水平。