Haacke E Mark, Liu Saifeng, Buch Sagar, Zheng Weili, Wu Dongmei, Ye Yongquan
Department of Radiology, Wayne State University, Detroit, MI, USA; School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada; Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China.
School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada.
Magn Reson Imaging. 2015 Jan;33(1):1-25. doi: 10.1016/j.mri.2014.09.004. Epub 2014 Oct 25.
Quantitative susceptibility mapping (QSM) is a new technique for quantifying magnetic susceptibility. It has already found various applications in quantifying in vivo iron content, calcifications and changes in venous oxygen saturation. The accuracy of susceptibility mapping is dependent on several factors. In this review, we evaluate the entire process of QSM from data acquisition to individual data processing steps. We also show preliminary results of several new concepts introduced in this review in an attempt to improve the quality and accuracy for certain steps. The uncertainties in estimating susceptibility differences using susceptibility maps, phase images, and T2* maps are analyzed and compared. Finally, example clinical applications are presented. We conclude that QSM holds great promise in quantifying iron and becoming a standard clinical tool.
定量磁化率成像（QSM）是一种用于量化磁化率的新技术。它已经在量化体内铁含量、钙化以及静脉血氧饱和度变化方面有了多种应用。磁化率成像的准确性取决于几个因素。在本综述中，我们评估了从数据采集到各个数据处理步骤的QSM全过程。我们还展示了本综述中引入的几个新概念的初步结果，试图提高某些步骤的质量和准确性。分析并比较了使用磁化率图、相位图像和T2*图估计磁化率差异时的不确定性。最后，给出了临床应用实例。我们得出结论，QSM在量化铁含量以及成为标准临床工具方面具有巨大潜力。
