肺泡蛋白沉积症所致的铺路石样表现：CT表现及病理基础
Crazy paving pattern caused by pulmonary alveolar proteinosis: CT findings and the pathologic basis.
作者信息
Luo Jianguang, Yang Dongyi, Zhou Shunke, Xiao Enhua, Chen Ping, Fan Songqing, Liu Jun
机构信息
Department of Radiology,Second Xiangya Hospital, Central South University, Changsha 410011, China.
出版信息
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2014 Sep;39(9):924-9. doi: 10.11817/j.issn.1672-7347.2014.09.010.
OBJECTIVE
To explore CT findings and pathologic basis of crazy paving pattern caused by pulmonary alveolar proteinosis.
METHODS
Twenty-four patients who were diagnosed pathologically as pulmonary alveolar proteinosis by transbronchial lung biopsy and bronchoalveolar lavage fluid from June 2006 to May 2012 were included in this retrospective study. All patients underwent a 64-slice CT of the lungs.
RESULTS
CT findings: crazy paving pattern was observed on CT imaging of all 24 patients. In 23 patients, crazy paving pattern displayed strip-shaped opacities with smooth edges, and there was a clear boundary between the pathological and normal lung tissues. The reticular opacities were connected with peripheral blood vessels and the branches were formed, and their diameters decreased slightly. Microscopically, hemangiectasis were seen in 17 patients.
CONCLUSION
Crazy paving pattern caused by pulmonary alveolar proteinosis displayed clear edges, and smooth reticular opacities, most of which were due to hemangiectasis of interlobular, interacinar and interalveolar septa. These findings of CT are helpful for the specific diagnosis of pulmonary alveolar proteinosis.
目的
探讨肺泡蛋白沉积症所致铺路石征的CT表现及病理基础。
方法
回顾性分析2006年6月至2012年5月间经支气管肺活检及支气管肺泡灌洗病理诊断为肺泡蛋白沉积症的24例患者。所有患者均行肺部64层CT检查。
结果
CT表现：24例患者CT图像均显示铺路石征。23例患者铺路石征表现为边缘光滑的条索状阴影，病变肺组织与正常肺组织界限清晰。网状阴影与周围血管相连并形成分支，其直径略有变细。镜下观察，17例患者可见血管扩张。
结论
肺泡蛋白沉积症所致铺路石征边缘清晰，网状阴影光滑，大部分是由于小叶间隔、腺泡间隔及肺泡间隔血管扩张所致。这些CT表现有助于肺泡蛋白沉积症的明确诊断。
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