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贵宾犬、拉布拉多寻回犬、泰国脊背犬和泰国班凯犬的正常临床视网膜电图参数。

Normal clinical electroretinography parameters for poodle, Labrador retriever, Thai ridgeback, and Thai Bangkaew.

作者信息

Sussadee Metita, Phavaphutanon Janjira, Kornkaewrat Kornchai, Thayananuphat Aree

机构信息

Center for Agricultural Biotechnology, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen Campus, Nakhon Pathom 73140, Thailand.

出版信息

J Vet Sci. 2015;16(1):67-74. doi: 10.4142/jvs.2015.16.1.67. Epub 2014 Sep 30.

Abstract

The purpose of the present study was to establish normal electroretinogram (ERG) parameters using 56 normal eyes of four dog breeds common in Thailand: poodle, Labrador retriever, Thai ridgeback, and Thai Bangkaew. Standard ERG findings were bilaterally recorded using a handheld multi-species ERG unit with an ERG-jet lens electrode for 28 dogs under preanesthesia with diazepam, anesthesia with propofol, and anesthesia maintenance with isoflurane. There were significant differences in the mean values of ERG amplitudes and implicit times among the four dog breeds (p < 0.05) except for the b-wave implicit time of the photopic 30 Hz flicker response with 3 cd.s/m(2) (p = 0.610). Out of the four breeds, Thai Bangkaew had the longest implicit time (p < 0.001) of scotopic low intensity responses, b-wave of scotopic standard intensity responses (3 cd.s/m(2)), a-wave of the higher intensity response (10 cd.s/m(2)), and a-wave of the photopic single flash response (3 cd.s/m(2)). For the b/a ratio, only the ratio of the Cone response was significantly different among the different breeds. In this summary, normal ERG parameters for four dog breeds were reported. Data from the investigation supported the hypothesis that determination of breed-specific limits of normality for ERG responses is necessary for individual clinics and laboratories.

摘要

本研究的目的是利用泰国常见的四个犬种(贵宾犬、拉布拉多寻回犬、泰国脊背犬和泰国班凯犬)的56只正常眼睛,建立正常视网膜电图(ERG)参数。使用手持式多物种ERG设备和ERG-jet透镜电极,对28只犬在使用地西泮进行预麻醉、丙泊酚进行麻醉以及异氟醚进行麻醉维持的情况下,双侧记录标准ERG结果。除了在3 cd.s/m(2)的明视30 Hz闪烁反应的b波隐含时间外(p = 0.610),四个犬种之间的ERG振幅和隐含时间的平均值存在显著差异(p < 0.05)。在这四个犬种中,泰国班凯犬在暗视低强度反应、暗视标准强度反应(3 cd.s/m(2))的b波、较高强度反应(10 cd.s/m(2))的a波以及明视单次闪光反应(3 cd.s/m(2))的a波方面,具有最长的隐含时间(p < 0.001)。对于b/a比值,只有不同犬种之间的视锥细胞反应比值存在显著差异。在此总结中,报告了四个犬种的正常ERG参数。该调查的数据支持了这样一种假设,即对于各个诊所和实验室而言,确定ERG反应的特定品种正常范围是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652d/4367151/5ad16064075f/jvs-16-67-g001.jpg

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