Laboratoire de Coprologie Fonctionnelle, APHP, GH Pitié-Salpêtrière Charles Foix, Université Paris Descartes, Paris, France.
Clin Microbiol Infect. 2014 Nov;20(11):1098-105. doi: 10.1111/1469-0691.12796.
Clostridium difficile infection is a leading cause of antibiotic-related and healthcare-related diarrhoea. In the past decade, faecal microbiota transplantation or transfer has attracted increasing interest as an effective treatment strategy for severe recurrent C. difficile infection, with a global success rate of >80%. However, experience with this procedure is limited by a lack of randomized trials supporting its efficacy and the lack of standardization of the procedure. This review will address the practical aspects of the protocol.
艰难梭菌感染是抗生素相关性和医疗保健相关性腹泻的主要原因。在过去的十年中，粪便微生物群移植或转移作为一种有效的治疗严重复发性艰难梭菌感染的策略引起了越来越多的关注，全球成功率>80%。然而，由于缺乏支持其疗效的随机试验以及该程序缺乏标准化，因此该程序的经验受到限制。这篇综述将讨论该方案的实际方面。
