印度一家三级护理教学医院老年患者潜在不适当用药情况
Utilization of potentially inappropriate medications in elderly patients in a tertiary care teaching hospital in India.
作者信息
Jhaveri Binit N, Patel Tejas K, Barvaliya Manish J, Tripathi Chandrabhanu
机构信息
Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat, India.
Department of Pharmacology, GMERS Medical College, Gotri, Vadodara, Gujarat, India.
出版信息
Perspect Clin Res. 2014 Oct;5(4):184-9. doi: 10.4103/2229-3485.140562.
AIM
To evaluate the use of potentially inappropriate medicines in elderly inpatients in a tertiary care teaching hospital.
MATERIALS AND METHODS
Retrospective analysis was performed for cases of elderly patients admitted between January 2010 and December 2010. Data on age, gender, diagnosis, duration of hospital stay, treatment, and outcome were collected. Prescriptions were assessed for the use of potentially inappropriate medications in geriatric patients by using American Geriatric Society Beer's criteria (2012) and PRISCUS list (2010).
RESULTS
A total of 676 geriatric patients (52.12% females) were admitted in the medicine ward. The average age of geriatric patients was 72.69 years. According to Beer's criteria, at least one inappropriate medicine was prescribed in 590 (87.3%) patients. Metoclopramide (54.3%), alprazolam (9%), diazepam (8%), digoxin > 0.125 mg/day (5%), and diclofenac (3.7%) were the commonly used inappropriate medications. Use of nonsteroidal anti-inflammatory drugs (NSAIDs) in heart and renal failure patients was the commonly identified drug-disease interaction. According to PRISCUS list, at least one inappropriate medication was prescribed in 210 (31.06%) patients.
CONCLUSION
Use of inappropriate medicines is highly prevalent in elderly patients.
目的
评估一家三级护理教学医院老年住院患者中潜在不适当药物的使用情况。
材料与方法
对2010年1月至2010年12月期间收治的老年患者病例进行回顾性分析。收集了年龄、性别、诊断、住院时间、治疗及转归等数据。采用美国老年医学会Beer标准（2012年）和PRISCUS清单（2010年）评估处方中老年患者潜在不适当药物的使用情况。
结果
内科病房共收治676例老年患者（女性占52.12%）。老年患者的平均年龄为72.69岁。根据Beer标准，590例（87.3%）患者至少开具了一种不适当药物。常用的不适当药物有甲氧氯普胺（54.3%）、阿普唑仑（9%）、地西泮（8%）、地高辛>0.125mg/天（5%）和双氯芬酸（3.7%）。心力衰竭和肾衰竭患者使用非甾体类抗炎药（NSAIDs）是常见的药物 - 疾病相互作用。根据PRISCUS清单，210例（31.06%）患者至少开具了一种不适当药物。
结论
不适当药物在老年患者中的使用非常普遍。
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