Alshehri Samah, Alshibani Mohannad, Magboul Ghaydaa, Albandar Albandari, Nasser Roaa, Yaqoub Roaya M, Alzuhayri Jumana, Aljabri Ahmed
Department of Pharmacy Practice, Faculty of Pharmacy, King Abdulaziz Univeristy, Jeddah 21589, Saudi Arabia.
Faculty of Pharmacy, University of Arizona, Tucson, AZ 85721, USA.
Geriatrics (Basel). 2020 Nov 21;5(4):97. doi: 10.3390/geriatrics5040097.
The aging process makes geriatric populations more prone to various chronic diseases. Such diseases require older patients to be on more medications than any other age group and make them more susceptible to adverse drug events related to potentially inappropriate medications (PIMs).
To identify the prevalence of potentially inappropriate medications among older people and explore the most commonly prescribed PIMs in hospitalized patients.
A retrospective study conducted in a large tertiary hospital among patients hospitalized in a 4 year period from January 2015 to December 2018.
The 2019 Beers Criteria were used to assess PIMs in all inpatient prescribed medications focusing on the first class (i.e., drug/drug class to be avoided in older adults).
The mean age was 75.17 ± 7.66 years. A total of 684 (80.6%) patients were prescribed at least one medication listed in the first-class category of the 2019 Beers Criteria. Top five drugs were proton pump inhibitors (40.3%), nonsteroidal anti-inflammatory drugs (10.2%), metoclopramide (9.3%), benzodiazepines (8.4%), and insulin (5.4%).
The prevalence of PIMs is high among older patients admitted to the hospital. More efforts are needed to investigate the potential reasons and develop action plans to improve concordance to Beers Criteria among healthcare providers.
衰老过程使老年人群更容易患各种慢性病。这类疾病要求老年患者服用的药物比其他任何年龄组都多，并且使他们更容易发生与潜在不适当用药（PIM）相关的药物不良事件。
确定老年人中潜在不适当用药的患病率，并探索住院患者中最常开具的PIM。
一项回顾性研究，在一家大型三级医院对2015年1月至2018年12月期间住院4年的患者进行。
使用2019年版《Beers标准》评估所有住院患者处方药物中的PIM，重点关注第一类（即老年人应避免使用的药物/药物类别）。
平均年龄为75.17±7.66岁。共有684名（80.6%）患者至少开具了一种2019年版《Beers标准》第一类中列出的药物。排名前五的药物是质子泵抑制剂（40.3%）、非甾体抗炎药（10.2%）、甲氧氯普胺（9.3%）、苯二氮䓬类药物（8.4%）和胰岛素（5.4%）。
入院老年患者中PIM的患病率很高。需要做出更多努力来调查潜在原因，并制定行动计划，以提高医疗服务提供者对《Beers标准》的依从性。
