Kong Ji Sun, Kim Mee-Seon, Lee Kyu-Yup
Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.
Department of Pathology, School of Medicine, Kyungpook National University, Daegu, Korea.
Korean J Audiol. 2014 Sep;18(2):89-92. doi: 10.7874/kja.2014.18.2.89. Epub 2014 Sep 16.
Cholesterol granulomas are benign granulomatous lesions caused by tissue reaction to a foreign body such as cholesterol crystals. These crystals have been are associated with pathological conditions of pneumatized spaces, including those causing inadequate aeration, obstruction of drainage, and hemorrhage in pneumatized spaces, and where materials trapping materials, such as hemosiderin or cholesterol become trapped, and then forming a cholesterol granuloma. Cholesterol granulomas are frequently found in the temporal bones, with the middle ear, mastoid caverna, and petrous apex being the most commonly affected sites. As there have been few reported cases of cholesterol granulomas presenting as a mass in the external acoustic canal (EAC), a cholesterol granuloma occluding the entire EAC in a pediatric patient is considered quite rare. We encountered a large cholesterol granuloma occupying the entire EAC, resulting in total EAC occlusion in a 12-year-old girl. The granuloma was diagnosed via medical imaging and surgically excised.
胆固醇肉芽肿是由组织对诸如胆固醇晶体等异物的反应引起的良性肉芽肿性病变。这些晶体与含气腔隙的病理状况相关,包括那些导致通气不足、引流受阻以及含气腔隙内出血的情况,并且在这些地方,诸如含铁血黄素或胆固醇等物质会被困住,进而形成胆固醇肉芽肿。胆固醇肉芽肿常见于颞骨,中耳、乳突腔和岩尖是最常受累的部位。由于外耳道肿块形式的胆固醇肉芽肿报道病例较少,小儿患者中完全阻塞外耳道的胆固醇肉芽肿被认为相当罕见。我们遇到一例占据整个外耳道的巨大胆固醇肉芽肿,导致一名12岁女孩的外耳道完全阻塞。该肉芽肿经医学影像诊断,并通过手术切除。