Department of Neurological and Movement Sciences, Anatomy and Histology Section, University of Verona, Strada le Grazie, 8, 37134, Verona, Italy,
J Neurol. 2015;262(4):806-13. doi: 10.1007/s00415-014-7518-1. Epub 2014 Oct 4.
Parkinson's disease is now considered a complex systemic disease also characterized by the occurrence of a variety of non-motor symptoms. Among them, a chemosensory impairment defined as a deficient olfactory performance is now acknowledged to be one of the prevalent symptoms since the early stages of the disease. Less clear are the incidence, extent and pathophysiology of taste function. The purpose of the present review is to summarize the state of the art in taste literature. To provide a better understanding of the available results, we will also discuss the different methods for taste evaluation and the other potential confounders to be addressed by future research.
帕金森病现在被认为是一种复杂的系统性疾病,其特征还包括多种运动外症状的发生。其中,一种化学感觉障碍,即嗅觉表现不佳,现已被认为是疾病早期的常见症状之一。味觉功能的发生率、程度和病理生理学尚不清楚。本文综述的目的是总结味觉研究的现状。为了更好地理解现有结果,我们还将讨论味觉评估的不同方法和未来研究中需要解决的其他潜在混杂因素。