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[维拉帕米治疗的耐力运动员高血压性左心室扩大的消退RR]

[Regression of hypertension-induced left heart enlargement in an endurance athlete treated with verapamil RR].

作者信息

Lehmann M, Dürr H, Keul J

机构信息

Medizinische Universitätsklinik Freiburg im Bresigau, Abt. Sport- und Leistungsmedizin.

出版信息

Z Kardiol. 1989 Jul;78(7):465-8.

PMID:2528244
Abstract

In October 1987, Stage II arterial hypertension, probably of primary genesis, was diagnosed in a 52-year-old male patient. There was marked left-ventricular hypertrophy (left-ventricular muscle mass 224g, corresponding to 2.99 g/kg: mass-volume ratio of the left ventricle 1.9 g/ml; end-diastolic septum thickness 15 mm, posterior wall thickness 13 mm). The patient is engaged in endurance sports for 5-12h each week and participates regularly in competitions. He was not advised to terminate athletic activities. The patient's submaximum performance (supine ergometry) is 3.3 watts per kg body weight. Under therapy with 2 x 240 g Verapamil per day, blood pressure decreased in the course of a year by 30/30 mm Hg at rest and 30/20 mm Hg at a specified exercise level. The left ventricular muscle mass decreased by about 70g, the mass-volume ratio normalized to 1.3 g/ml.

摘要

1987年10月,一名52岁男性患者被诊断为II期动脉高血压,可能为原发性。存在明显的左心室肥厚(左心室肌肉质量224克,相当于2.99克/千克;左心室质量-容积比1.9克/毫升;舒张末期室间隔厚度15毫米,后壁厚度13毫米)。该患者每周进行5至12小时的耐力运动,并定期参加比赛。未建议他停止体育活动。该患者的次最大运动能力(仰卧测力计测试)为每千克体重3.3瓦。在每天服用2×240克维拉帕米的治疗下,一年中静息血压下降了30/30毫米汞柱,在特定运动水平下血压下降了30/20毫米汞柱。左心室肌肉质量减少了约70克,质量-容积比恢复正常至1.3克/毫升。

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