Kirik O V, Sukhorukova E G, Alekseeva O S, Korzhevskiĭ D É
Morfologiia. 2014;145(2):67-9.
The goal of the study was to identify the subependymal microglial cells of the III ventricle of the rat brain and to determine their structural characteristics. The sections of the brain of intact Wistar (n = 3) and Sprague-Dawley (n = 3) male rats were studied using the methods of immunocytochemistry and confocal laser microscopy. Subependymal microglia of the III ventricle was found to be a constantly present cell population. Two types of subependymal microgliocytes were identified--spindle-like and basket cells. Their processes penetrate the ependymal layer and reach its surface, thus contacting the cerebrospinal fluid (CSF), which suggests a possible participation of these cells in the structure of CSF-brain barrier.
该研究的目的是识别大鼠脑第三脑室的室管膜下小胶质细胞,并确定其结构特征。使用免疫细胞化学和共聚焦激光显微镜方法,对完整的Wistar(n = 3)和Sprague-Dawley(n = 3)雄性大鼠的脑切片进行了研究。发现第三脑室的室管膜下小胶质细胞是一个持续存在的细胞群体。识别出两种类型的室管膜下小胶质细胞——纺锤状细胞和篮状细胞。它们的突起穿透室管膜层并到达其表面,从而与脑脊液(CSF)接触,这表明这些细胞可能参与脑脊液-脑屏障的结构。